This paper investigates Canada’s endeavor for carbon neutrality by 2050 and its strategic response to the European energy crisis resulting from the Russia-Ukraine war. With a significant potential for hydrogen production, Canada’s hydrogen exports to Europe are poised to reshape its hydrogen supply chains downstream (HSCD). Through a systematic review of 39 papers published before October 2023, our examination explores HSCD components, decision levels, and sustainability perspectives. Consequently, we offer recommendations for scientific, legislative, and industrial sectors for forward horizons. Additionally, this study proposes future research avenues for similar systematic review papers.