2015
DOI: 10.4132/jptm.2015.06.11
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A Review of Inflammatory Processes of the Breast with a Focus on Diagnosis in Core Biopsy Samples

Abstract: Inflammatory and reactive lesions of the breast are relatively uncommon among benign breast lesions and can be the source of an abnormality on imaging. Such lesions can simulate a malignant process, based on both clinical and radiographic findings, and core biopsy is often performed to rule out malignancy. Furthermore, some inflammatory processes can mimic carcinoma or other malignancy microscopically, and vice versa. Diagnostic difficulty may arise due to the small and fragmented sample of a core biopsy. This… Show more

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Cited by 58 publications
(50 citation statements)
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References 58 publications
(79 reference statements)
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“…Microscopy of six core‐biopsy samples revealed stromal fibrosis with epithelioid fibroblasts, without any sign of atypia. Epithelioid fibroblasts are a particular cell type, which has been considered distinctive of DM . Furthermore, mild perivascular lymphocytic infiltration surrounding ducts, lobules and small vessel was described in these samples.…”
Section: Case Reportmentioning
confidence: 78%
“…Microscopy of six core‐biopsy samples revealed stromal fibrosis with epithelioid fibroblasts, without any sign of atypia. Epithelioid fibroblasts are a particular cell type, which has been considered distinctive of DM . Furthermore, mild perivascular lymphocytic infiltration surrounding ducts, lobules and small vessel was described in these samples.…”
Section: Case Reportmentioning
confidence: 78%
“…This pattern consists of granulomas with epithelioid histiocytes, neutrophils, multinucleated giant cells, lymphocytes, and plasma cells. This picture is clearly different from that of fat necrosis, in which foamy histiocytes are predominant and neutrophils are absent [36]. Also, duct ectasia is characterized by foamy histiocytes and the absence of neutrophils and epithelioid histiocytes [37].…”
Section: Discussionmentioning
confidence: 99%
“…Non‐puerperal subareolar breast abscess accounts for 1–2% of all symptomatic breast conditions. It is a recurring disease with a strong link to obesity, diabetes and cigarette smoking . This is also known as squamous metaplasia of lactiferous ducts (SMOLD) .…”
Section: Non‐puerperal Subareolar Breast Abscessmentioning
confidence: 99%
“…Mammary duct ectasia, also known as plasma cell mastitis is usually seen in elderly women who present with nipple retraction, discharge and, on occasion, a palpable mass . Ultrasound shows dilated ducts (>2 mm in diameter) containing echogenic debris with increased colour Doppler flow in the periductal breast tissue . This can be an incidental finding on mammography, demonstrating characteristic dense, uniform needle‐like calcifications, arranged in lines radiating from the nipple, due to calcified inspissated contents within the duct (Fig.…”
Section: Mammary Duct Ectasiamentioning
confidence: 99%
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