A review of neglected tropical diseases: filariasis

Abstract

Filariasis is result of parasitic infection caused by three specific kinds of round worm. Lymphatic filariasis is found in under developed region of South America, Central Africa, pacific and Caribbian. It has been found for centuries, with main symptoms as elephant like swelling of the arms, legs and genitals. It is estimate that 120 millions peoples in the world have lymphatic filariasis. The spread of diseases and the challenge encountered in its management are discussed along with a review on drugs against filariasis in this article. Detail on clinical effect of drugs on the infection, safety profile, status in clinical practices and drug resistances are also covered.

A Novel Dirofilaria Species Causing Human and Canine Infections in Hong Kong

“…The commonest Dirofilaria species causing human infections are D. repens and D. immitis, which are canine pathogens (27). Human D. repens infections are reported mainly in Europe and Asia, while human D. immitis infections are more prevalent in North America (6,10). Other noncanineassociated species that occasionally cause human infections include D. tenuis (from raccoons), D. ursi (from bears), D. subdermata (from porcupines), and D. striata (from bobcats) (4,6,27,33).…”

Phylogenetic analysis of eyeworm (Oxyspirura petrowi) in northern bobwhite (Colinus virginianus) based on the nuclear 18S rDNA and mitochondrial cytochrome oxidase 1 gene (COX1)

“…While the filarial nematodes W. bancrofti and B. pahangi cause lymphatic filariasis in the definitive hosts, L. loa causes loaiasis (Chandy et al 2011;Tan et al 2011). Typically found in humans of west and central Africa, L. loa is transmitted through a deerfly (Chrysops spp.)…”

A bipolar disorder patient becoming asymptomatic after adjunctive anti-filiarasis treatment: a case report

“…Filariasis is a parasitic disease acting ruthlessly via mosquitos in regions of Asia, Africa, Central, South America and Pacific Island nations, with more than 120 million people infected. 90% of this infection is caused by W. bancrofti with about 80 countries known to be endemic areas [7]. The most important filarial disease for humans is lymphatic filariasis in which the adult worms are present in the lymphatic system [7].…”

“…90% of this infection is caused by W. bancrofti with about 80 countries known to be endemic areas [7]. The most important filarial disease for humans is lymphatic filariasis in which the adult worms are present in the lymphatic system [7]. Males are more frequently affected (sex ratio 10:1) in their third or 4 th decade [7].…”

“…The most important filarial disease for humans is lymphatic filariasis in which the adult worms are present in the lymphatic system [7]. Males are more frequently affected (sex ratio 10:1) in their third or 4 th decade [7]. The incubation period from mosquito bite may be comprised between 4 weeks and more than six months [7].…”