A Review of Pathological Biomineral Analysis Techniques and Classification Schemes

Giannossi, Maria Luigia; Summa, Vito

doi:10.5772/34861

Cited by 8 publications

(13 citation statements)

References 73 publications

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“…Furthermore, more than half of individuals diagnosed with urinary calculi will see reoccurrence of the disease within 5-10 years [2]. Urinary calculi consist of hard masses, with surfaces varying in smoothness and irregularities, and are located primarily within the kidney [3]. Although the exact mechanism behind urinary calculi formation is not completely understood, several etiologic factors have been successfully identified.…”

Section: Introductionmentioning

confidence: 99%

“…Although the exact mechanism behind urinary calculi formation is not completely understood, several etiologic factors have been successfully identified. Such factors include genetic influence, super-saturated urine, epithelium alterations in the renal papilla, and food habits combined with lifestyle [2,3]. The disease is very likely to cause significant pain for the individual, leading to a substantial negative impact on society, work environments, and healthcare systems.…”

Section: Introductionmentioning

confidence: 99%

“…Whilst no causal connection has been discovered between urolithiasis and the aforementioned diseases, treatment of one of the disorders may prevent the occurrence of some of the others [2,13,14] The composition of urinary calculi can be divided into in two categories: the organic matrix and the mineral component. The organic matrix consists primarily of amino acids, carbohydrates, and lipids, while the mineral component assumes various identities depending on the classification of the calculi [3]. Over 80% of urinary calculi contain calcium compounds, with calcium oxalate and calcium phosphate being the primary contributors [3].…”

Section: Introductionmentioning

confidence: 99%

“…The organic matrix consists primarily of amino acids, carbohydrates, and lipids, while the mineral component assumes various identities depending on the classification of the calculi [3]. Over 80% of urinary calculi contain calcium compounds, with calcium oxalate and calcium phosphate being the primary contributors [3]. The chemical components of the remaining 20% are of either uric acid or struvite origin, with a small percentage falling into several different classifications, such as those having cystine and drug related origins [3] When the urine's pH balance becomes too acidic or too basic, this causes accumulation of minerals that form kidney stones.…”

Section: Introductionmentioning

confidence: 99%

“…Over 80% of urinary calculi contain calcium compounds, with calcium oxalate and calcium phosphate being the primary contributors [3]. The chemical components of the remaining 20% are of either uric acid or struvite origin, with a small percentage falling into several different classifications, such as those having cystine and drug related origins [3] When the urine's pH balance becomes too acidic or too basic, this causes accumulation of minerals that form kidney stones. Researchers suspect that high protein diets might also cause stone formation since, during digestion of proteins, acids are created.…”

Section: Introductionmentioning

confidence: 99%

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Comparative spectroscopic analysis of nordihydroguaiaretic acid and related natural products to inhibition of calcium oxalate calculi

2019

Biointerface Res Appl Chem

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The prevalence of urolithiasis is still increasing worldwide. The goal of this study is to achieve a better understanding, from a comparative spectroscopic perspective, of the differences provided by chemical and natural products to the inhibitory processes of calculi formation. The research presented here places primary emphasis on the assessment of nordihydroguaiaretic acid (NDGA), the main chemical extract of the plant Larrea Tridentata, as a preventative to calcium oxalate crystal formation. It is also a logical continuation of our previous efforts using a traditional medicine approach to study such prevention. Complementary Raman and Fourier transformed infrared (FTIR) absorption analysis were used to provide a complete overview of morphological changes of calcium oxalate crystals, which were grown without and with the addition of NDGA at different concentrations. A gel diffusion technique was employed for sample preparation. Our results from both Raman and FTIR spectroscopies demonstrate that no structural transformation from a monohydrate to dehydrate occurs upon crystallization with NDGA, as we previously reported for the use of the natural plant infusion. Calculi synthesized with NDGA shows a distorted monohydrate morphology. Different effects inhibitory to calcium oxalate calculi formation are observed and analyzed here using chemical and natural extracts. If magnesium is the key to this difference, this study confirms its importance, not only in hundreds of metabolic pathways, but also in nephrological ones.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Comparative spectroscopic analysis of nordihydroguaiaretic acid and related natural products to inhibition of calcium oxalate calculi

2019

Biointerface Res Appl Chem

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Nanominerals and Nanomaterials Utilized in Pharmacy and Therapeutics

Gomes

Santos

Amaral

2021

Minerals Latu Sensu and Human Health

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The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2021 This work is subject to copyright. All rights are solely and exclusively licensed by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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May a comprehensive mineralogical study of a jackstone calculus and some other human bladder stones unveil health and environmental implications?

Mercurio

Izzo

Gatta

et al. 2021

Environ Geochem Health

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A Review of Pathological Biomineral Analysis Techniques and Classification Schemes

Cited by 8 publications

References 73 publications

Comparative spectroscopic analysis of nordihydroguaiaretic acid and related natural products to inhibition of calcium oxalate calculi

Comparative spectroscopic analysis of nordihydroguaiaretic acid and related natural products to inhibition of calcium oxalate calculi

Nanominerals and Nanomaterials Utilized in Pharmacy and Therapeutics

May a comprehensive mineralogical study of a jackstone calculus and some other human bladder stones unveil health and environmental implications?

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