A review of phytotherapy of acne vulgaris: Perspective of new pharmacological treatments

Azimi, Hanieh; Fallah-Tafti, Mehrnaz; Khakshur, Ali Asghar; Abdollahi, Mohammad

doi:10.1016/j.fitote.2012.03.026

Cited by 69 publications

(47 citation statements)

References 54 publications

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“…Shah et al [14] have also recorded the antibacterial activity of ethanol extract of pulp of C. guianensis and found susceptibility of B. subtilis (18 mm) compared to S. aureus (13 mm) and E. coli (12 mm). A similar study was also done by Azimi et al [15]. Regina et al [16] Reported the antibacterial property of solvent extracts of fruit rind of C. guianensis.…”

Section: Antibacterial Activitysupporting

confidence: 59%

Couroupita Guianensis: The Reservoir of Medicinal Compounds of Human Welfare

Moorthi

S²

2017

Asian J Pharm Clin Res

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Medicinal plants play a role in the traditional form of providing relief to several diseases. Couroupita guianensis is also a type of medicinal plant which has antibacterial, antimycobacterial, antimicrobial, antioxidant, antitumor, antiulcer, antinociceptive, anthelmintic, antifertility, and antifungal activities. The chemical constituent of C. guianensis such as indirubin serves as an antibacterial and antifungal agent because it particularly cures fungal diseases. It is active for the treatment of chronic myelocytic leukemia. The extract of isatin from the flower of C. guianensis is also a chemical component that has been used as prophylactic agent, prevents free radial-induced cancer, acts as a chemotherapeutic agent to kill cancer cells, and it has antioxidant (act as major defense) and anticancer activities against human promylocytic leukemia 60 cells. The extract of chloroform of fruit of C. guianensis shows good antimicrobial activity but low antimycobacterial activity. The plant extract of C. guianensis is equipotent to standard drugs such as paracetamol in its analgesic activity and indomethacin in its anti-inflammatory activity.

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Section: Antibacterial Activitysupporting

confidence: 59%

Couroupita Guianensis: The Reservoir of Medicinal Compounds of Human Welfare

Moorthi

S²

2017

Asian J Pharm Clin Res

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“…Some of this work appears to indicate that plants such as Camellia sinensis (green/black tea) show 5α-hydroxidase and anti-inflammatory activity [14], jojoba oil may reduce inflammatory- and non-inflammatory-lesion counts [15], and tea tree ( Melaleuca alternifolia ) oil significantly reduces total lesion counts and acne severity index as compared to placebo [16]. …”

Section: Discussionmentioning

confidence: 99%

Case Reports of Acne and Homeopathy

Nwabudike¹

2018

Complement Med Res

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Background: Acne vulgaris is a self-limiting disorder of the pilosebaceous unit. The aesthetic aspect of the disorder may provoke depression and diminish the quality of life. A number of agents are used for acne treatment, e.g., retinoids, antibiotics, benzoic acid, azelaic acid, and hormones. These agents have side-effects, sometimes severe ones. Case Reports: Presented are 2 cases of severe acne treated with individualized homeopathic medicines. Both patients were treated using the classical method of homeopathy, i.e., a single medicine based on the patient's individual characteristics was prescribed. The cases were documented photographically at onset and during the course of treatment. Both patients went into remission following treatment, and long-term follow-up suggested that the therapy remained efficacious long after cessation of treatment. No significant side effects were noted. Conclusions: Homeopathic medicines may be useful as stand-alone treatment of patients with severe acne vulgaris. A case series suggested a remission rate of more than 80% using individualized homeopathic treatment. The treatment remained efficacious long after cessation and is not accompanied by significant side-effects. It is to be hoped that this presentation will stimulate research interest into homeopathic medicines as stand-alone or adjunct treatments of acne.

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“…Immune response followed by release of infl ammatory mediators in skin 4. Hyperproliferation of keratinocytes mimicking type IV hypersensitivity response [ 75 -77 ] Further, these lesions are reported to harbour other bacterial strains like Pityrosporum ovale and Staphylococcus epidermidis [ 77 ]. Previously, considering the bacterial origin of the disease, antibacterial agents were used as monotherapy, both orally and topically, but it resulted in development of resistant bacterial strains desiring a more effective treatment regimen.…”

Section: Antiacne Nanotherapeuticsmentioning

confidence: 99%