[2-(methacryloyloxy) ethyl] trimethylammonium chloride (MAETMAC) was grafted onto the casein backbone using the microwave-assisted technique. It was studied as a bio-based wood binding adhesive for fabrication of single standard lap joints. The hyper branched polymer network formed post grafting facilitated strong adhesion and enhanced the water holding capacity of the developed adhesive. The universal testing machine (UTM) was used to study the failure shear stress. The self-separation time for each grafted protein grade was reported as a study of water resistivity of the adhesive. The programmability of the properties – ‘failure shear stress’ and ‘self-separation time’ were controllable at the molecular level in terms of percentage grafting.