A review of the association between osteoporosis and alveolar ridge augmentation

Özgür, Erdoğan; Shafer, David; Taxel, Pamela; Freilich, Martin

doi:10.1016/j.tripleo.2007.04.008

Cited by 60 publications

(70 citation statements)

References 101 publications

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“…While cortical bone cannot be adequately evaluated at the anterior margin of ramus and in maxilla, the alveolar crest residual ridge and alveolar bone density show a significant relationship to total body calcium and regional bone loss. 10 Recent studies show alteration of trabecular bone as a result of low bone mineral density and osteoporosis in dental radiographs, 11 while a marked porosity and erosion of mandibular cortex especially below the mental foramen has been strongly associated with reports of low bone mineral content and osteoporotic fractures 12 . Mandibular trauma fractures with highest incidences are seen in the sites of parasymphysis, body, condyle and angle.…”

Section: Introductionmentioning

confidence: 99%

Preservation and promotion of bone formation in the mandible as a response to a novel calcium‐phosphate based biomaterial in mineral deficiency induced low bone mass male versus female rats

Rajsri

Naula

Mijares

et al. 2016

J Biomedical Materials Res

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Calcium and other trace mineral supplements have previously demonstrated to safely improve bone quality. We hypothesize that our novel calcium-phosphate based biomaterial (SBM) preserves and promotes mandibular bone formation in male and female rats on mineral deficient diet (MD). Sixty Sprague-Dawley rats were randomly assigned to receive one of three diets (n = 10): basic diet (BD), MD or mineral deficient diet with 2% SBM. Rats were sacrificed after 6 months. Micro-Computed Tomography (μCT) was used to evaluate bone volume and 3D-microarchitecture while microradiography (Faxitron) was used to measure bone mineral density from different sections of the mandible. Results showed that bone quality varied with region, gender and diet. MD reduced bone mineral density (BMD) and volume and increased porosity. SBM preserved BMD and bone mineral content (BMC) in the alveolar bone and condyle in both genders. In the alveolar crest and mandibular body, while preserving more bone in males, SBM also significantly supplemented female bone. Results indicate that mineral deficiency leads to low bone mass in skeletally immature rats, comparatively more in males. Furthermore, SBM administered as a dietary supplement was effective in preventing mandibular bone loss in all subjects. This study suggests that the SBM preparation has potential use in minimizing low peak bone mass induced by mineral deficiency and related bone loss irrespective of gender.

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Section: Introductionmentioning

confidence: 99%

Preservation and promotion of bone formation in the mandible as a response to a novel calcium‐phosphate based biomaterial in mineral deficiency induced low bone mass male versus female rats

Rajsri

Naula

Mijares

et al. 2016

J Biomedical Materials Res

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“…6 An increased rate of complications have been described in the literature, and include complications such as resorption, non-integration, delayed healing time of the bone graft, and even implant failure in the augmented bone in patients and animals with oestrogen deficiency. 21 However, some studies that have used autolyzed antigen-extracted allogeneic bone grafts, 22 synthetic particulate bone grafts, 23 bone grafts with tooth ash and plaster of Paris mixture, 24 autogenous bone grafts 25,26 and bovine bone grafts 27 have controversial results, suggesting that this is a topic that has not yet been clearly elucidated.…”

Section: Introductionmentioning

confidence: 99%

Effects of oestrogen deficiency and 17β-estradiol therapy on bone healing in calvarial critical size defects treated with bovine bone graft

Almeida¹,

Bosco²,

Faleiros³

et al. 2015

Archives of Oral Biology

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“…However, despite a reduced success rate, unfavorable systemic conditions are not always absolute contraindications for bone augmentation and dental implant placement [5].…”

Section: Introductionmentioning

confidence: 99%

Implantes dentários em uma paciente com Doença de Paget: relato de caso

Amaral

Falcão

Miranda

et al. 2015

Rev. Odonto Ciênc. (Online)

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Objective: Paget's disease (PD) is a metabolic bone disease characterized by increased bone resorption followed by excessive, unregulated bone formation. While its etiology remains elusive, several genetic and environmental factors have been implicated. PD results in weakened bone strength and abnormal bone architecture, which may be unfavorable for the placement of osseointegrated dental implants. Herein, we describe a patient with PD who received dental implants. Case description: An 86-year-old woman diagnosed with PD and treated with oral bisphosphonates, was referred for implant treatment. Four dental implants were fixed in the anterior mandible, and all implants presented good primary stability. The patient was followed for a period of 6 years. No clinical mobility or signs of looseness were observed, and the implants were successfully osseointegrated. Conclusion: We conclude that the use of bisphosphonates in PD can be an important role in the insertion and osseointegration of dental implants. However, additional research is needed to confirm these findings.Key words: Paget's disease; dental implants; bisphosphonates.Implantes dentários em uma paciente com Doença de Paget: relato de caso Resumo Objetivo: A doença de Paget (DP) é uma desordem óssea metabólica caracterizada por uma reabsorção óssea aumentada seguida por um excesso de formação de osso não regulada. Embora sua etiologia permaneça indefinida, vários fatores genéticos e ambientais têm sido implicados. A DP resulta em força óssea enfraquecida e arquitetura óssea anormal, que pode ser desfavorável para a colocação de implantes dentários osseointegrados. No presente trabalho, relata-se um caso de uma paciente com DP que recebeu implantes dentários. Descrição do caso: Uma mulher de 86 anos de idade com diagnóstico de DP e tratada com bisfosfonatos orais foi encaminhada para tratamento com implantes. Quatro implantes dentários foram fixados em região anterior da mandíbula e todos os implantes apresentaram boa estabilidade primária. O acompanhamento clínico da paciente foi feito por um período de 6 anos. Não foram observados mobilidade clínica ou sinais de frouxidão e os implantes foram com sucesso osseointegrados. Conclusão: Concluímos que o uso de bisfosfonatos na DP pode ter um papel importante na inserção e na integração óssea de implantes dentários. No entanto, pesquisas adicionais são necessárias para confirmar estes resultados.Palavras-chave: doença de Paget; implantes dentários; bisfosfonatos. 126Rev Odonto Cienc 2014;29(4):125-128 Dental implants and Paget's disease | Amaral et al.

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A review of the association between osteoporosis and alveolar ridge augmentation

Cited by 60 publications

References 101 publications

Preservation and promotion of bone formation in the mandible as a response to a novel calcium‐phosphate based biomaterial in mineral deficiency induced low bone mass male versus female rats

Preservation and promotion of bone formation in the mandible as a response to a novel calcium‐phosphate based biomaterial in mineral deficiency induced low bone mass male versus female rats

Effects of oestrogen deficiency and 17β-estradiol therapy on bone healing in calvarial critical size defects treated with bovine bone graft

Implantes dentários em uma paciente com Doença de Paget: relato de caso

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