A Review of the Effects of Vitamin E in Ovarian Cancer

Abstract

Vitamin E is made up of two substances, tocopherols (TOCs) and tocotrienols (TCTs). These substances are present in four different subtypes namely alpha, beta, delta and gamma and these subtypes differs in their chemical structures. Vitamin E has been made known to exert anticancer effects for decades-long ago. This vitamin, which is also a well-known lipid-soluble antioxidant, has been extensively studied and its effects on cancer cells progressions are widely reported. These include its effects on the progressions of the breast, cervix, colon, liver, lung, pancreas, prostate, skin, and stomach cancers. Despite the widely available reports on vitamin E as an anticancer, the particular reports on the effects of this vitamin for reproduction in ovarian cancer are remarkably limited. Hence, this review is written to provide a summary of the reported effects from the studies published between the year 2010-2020 and the possible future research on vitamin E in ovarian cancer. This review will contribute to a more organized finding on the effects of vitamin E and ovarian cancer.