A Review of the Effects of the COVID-19 Pandemic on Children and Adolescents’
Mental Health

Omoleye, Damilola Deborah; Abidakun, Oluwayemisi Olubukola; Akinje, Rachael Oluwadamilola; Ademuyiwa, Oluwaseun Hannah; Fasogbon, Beatrice Mofoluwaso

doi:10.2174/1573396319666230213104546

Cited by 3 publications

(2 citation statements)

References 69 publications

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“…These disorders typically develop before the age of 14 ( 2 ) and are associated with a range of short- and long-term consequences, including reduced quality of life, increased psychiatric and somatic comorbidity, disability, loss of education and eventually work, suicide and reduced life-span ( 3 , 4 ). Rates of anxiety and depression in children and adolescents have increased following the Covid-19 pandemic ( 5 ) due to factors such as social isolation, ( 6 ), time away from school and decreased physical activity ( 7 , 8 ). Not surprisingly, the current situation among children and adolescents is regarded as a major health crisis ( 9 ).…”

Section: Introductionmentioning

confidence: 99%

The effect of physical activity on anxiety symptoms among children and adolescents with mental health disorders: a research brief

Anker,

Bøe Sture,

Hystad

et al. 2024

Front. Psychiatry

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BackgroundAnxiety is prevalent among children and adolescents (termed youths), and leads to reduced quality of life, disability, loss of education and reduced life-span. Physical activity has shown promising effects on symptoms of anxiety in adult populations, and an increasing amount of research has also demonstrated some effect in youth. However, physical activity is not widely used in youth mental health care, and research is very limited.Methods/designThis single arm, pre-post study explores the effect of a manualized physical activity-based 14-session intervention termed Confident, Active and Happy Youth. Participants are youth attending specialized mental health care (N=51, M age = 13.4, SD = 2.2). Changes in anxiety symptoms are examined using mixed models with residual maximum likelihood (REML). The potential effect of anxiety subtype differences, participant age, comorbidity, and time spent in out-patient care are explored.ResultsYouths did not report any effect on anxiety symptoms after participation in CAHY, however, their parents report a significant reduction in youth’s anxiety symptoms in general (b = -0.11, 95%, CI: -0.21 to -0.01) and specifically for social phobia (b = -0.19, 95% CI: -0.35 to -0.03). Age and comorbidity showed no significant effect on anxiety symptoms post treatment. Prior treatment time in youth mental health care demonstrated inconclusive results.ConclusionThe study finds initial evidence of symptomatic change in a clinical population of youth’s receiving a physical activity-based intervention. Our research provides preliminary support for physical activity as a supplementary treatment method for mental health disorders among youths.Clinical Trial Registrationclinicaltrials.gov, NCT05049759

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Section: Introductionmentioning

confidence: 99%

The effect of physical activity on anxiety symptoms among children and adolescents with mental health disorders: a research brief

Anker,

Bøe Sture,

Hystad

et al. 2024

Front. Psychiatry

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“…Comparisons between the pre-and post-Pathway Preparation survey data indicated a massive improvement in students' awareness of their post-secondary life options, including colleges, trade schools, apprenticeships, and careers (Figure 7). pandemic and its lingering consequences have taken a drastic toll on the mental well-being of students across the United States and abroad (Omoleye et al, 2023;Schaeffer, 2022). At…”

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confidence: 99%

An investigation into pathway preparation and student motivation

Blaisdell

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Without the support of my family, friends, colleagues, and mentors, this project would not have been possible. I am profoundly grateful for the network of support I have had backing me at each stage of my continuing education and each milestone of this project.Mom, Dad, Ariana, and Nonni, you have always been there to support me in everything that I pursue with unconditional love and guidance. You have all taught me what it means to put others beyond yourself.Casey, I will always be indebted to the sacrifices you made to ensure I completed this project. You personally guaranteed that I truly had nothing to worry about besides this work, which allowed it to thrive and develop to its full capacity.Dr. Boozang, without your continued support, I could not imagine how this project would be possible. At each stage of drafting, planning, revising, and more, you were there to offer guidance and expertise which allowed me to extend beyond what I thought I was capable of.Dr. Serig, I am grateful for all of your contributions in pushing the scope and depth of this project. It is hard to imagine this project without your timely and rigorous feedback as a second reader.Dr. Gebhard, thank you so much for continuing your commitment to my academic growth. It's hard to believe that you were my professor for my first-ever course in the field of education and now you're my third reader for my dissertation. Thank you for everything, Meg.Lastly, I am deeply appreciative of everyone who was there for me in my journey. My family, friends, students, colleagues, and everyone who was there rooting for me along the way have made all the difference. All of the major and minor forms of support did not go unrecognized or unappreciated. 4 DedicationsTo my family, the foundation of my life. I love you, Mom, Dad, Ariana, Nonni, Papa, and Daisy.

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Identifying key biomarkers and therapeutic candidates for post-COVID-19 depression through integrated omics and bioinformatics approaches

Zhou,

Yang,

Zhou

et al. 2024

Translational Neuroscience

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Introduction Depression, the leading cause of disability worldwide, is known to be exacerbated by severe acute respiratory syndrome coronavirus 2 infection, worsening coronavirus disease 2019 (COVID-19) outcomes. However, the mechanisms and treatments for this comorbidity are not well understood. Methods This study utilized Gene Expression Omnibus datasets for COVID-19 and depression, combined with protein–protein interaction networks, to identify key genes. Gene ontology and Kyoto Encyclopedia of Genes and Genomes analyses were performed to understand gene functions. The CIBERSORT algorithm and NetworkAnalyst were used to examine the relationship of immune cell infiltration with gene expression and to predict transcription factors (TFs) and microRNAs (miRNAs) interactions. The Connectivity Map database was used to predict drug interactions with these genes. Results TRUB1, PLEKHA7, and FABP6 were identified as key genes enriched in pathways related to immune cell function and signaling. Seven TFs and nineteen miRNAs were found to interact with these genes. Nineteen drugs, including atorvastatin and paroxetine, were predicted to be significantly associated with these genes and potential therapeutic agents for COVID-19 and depression. Conclusions This research provides new insights into the molecular mechanisms of post-COVID-19 depression and suggests potential therapeutic strategies, marking a step forward in understanding and treating this complex comorbidity.

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A Review of the Effects of the COVID-19 Pandemic on Children and Adolescents’ Mental Health

Cited by 3 publications

References 69 publications

The effect of physical activity on anxiety symptoms among children and adolescents with mental health disorders: a research brief

The effect of physical activity on anxiety symptoms among children and adolescents with mental health disorders: a research brief

An investigation into pathway preparation and student motivation

Identifying key biomarkers and therapeutic candidates for post-COVID-19 depression through integrated omics and bioinformatics approaches

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