A review of the worldwide prevalence of vitiligo in children/adolescents and adults

Krüger, Christian; Schallreuter, Karin U.

doi:10.1111/j.1365-4632.2011.05377.x

Cited by 430 publications

(348 citation statements)

References 46 publications

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“…Consistent with this observation, vitiligo prevalence has previously been found to be higher in dark-skinned individuals (Sheth, Guo, & Qureshi, 2013). Low prevalence among Europeans is reinforced by large studies from Italy (0.17%), France (0.28%), and Denmark (0.12%), while higher prevalence was found in the United States (0.49%), Mexico (0.21%), Egypt (1.22%), Iran (0.60%), India (1.13%), China (1.9%)], and Australia (1.2%) (Kruger & Schallreuter, 2012).…”

Section: Prevalence Of Vitiligo In Brazil-a Population Surveymentioning

confidence: 98%

Prevalence of vitiligo in Brazil—A population survey

Castro

Miot

2018

Pigment Cell Melanoma Res

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Section: Prevalence Of Vitiligo In Brazil-a Population Surveymentioning

confidence: 98%

Prevalence of vitiligo in Brazil—A population survey

Castro

Miot

2018

Pigment Cell Melanoma Res

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“…Vitiligo is an acquired disorder of melanin pigmentation that affects about 1% of the world population [1]. The onset of this disease is seen before 15-years of age in majority of cases.…”

Section: Introductionmentioning

confidence: 99%

Targeted NBUVB Phototherapy in Childhood Vitiligo: A Study in 35 Children

Majid¹

2014

Pigmentary Disorders

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“…It occurs clinically by the appearance of well-circumscribed, asymptomatic, white macules following the loss of functional melanocytes in the epidermis (1). The prevalence rate of vitiligo ranges from 0.06% to 2.28% in the population (2). The main etiopathogenesis of vitiligo is multifactorial.…”

Section: Introductionmentioning

confidence: 99%

Investigation into the frequency of Helicobacter pylori infection with carbon 14 urea breath test in patients with vitiligo

Rifaioğlu¹,

Aydogan²,

Şen³

et al. 2014

Turk J Med Sci

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IntroductionVitiligo is an acquired depigmenting skin disorder. It occurs clinically by the appearance of well-circumscribed, asymptomatic, white macules following the loss of functional melanocytes in the epidermis (1). The prevalence rate of vitiligo ranges from 0.06% to 2.28% in the population (2). The main etiopathogenesis of vitiligo is multifactorial. According to various pathophysiological theories, it may be associated with autoimmunity, neurogenic dysregulation, autocytotoxicity, biochemical dysregulation, oxidative stress, and weak melanocyte viability (1,(3)(4)(5)(6). Several potentially environmental factors such as infectious agents appear to be related with vitiligo (7-9).Helicobacter pylori (HP) is a major health problem affecting about 50% of the world population (10). Gastric ulceration and carcinogenesis are associated with HP infection (11). HP infection has been linked to various autoimmune dermatological diseases, such as alopecia areata, Behçet's disease, chronic urticaria, pruritus, psoriasis, and rosacea (12-17). The frequency of HP has not been studied in patients with vitiligo. Noninvasive tests such as the carbon 13 or carbon 14 (C14) urea breath test (UBT), stool antigen tests, and serology are used to detect HP infection (18). In this study, we used the C14 UBT to detect the frequency of HP infection in patients with vitiligo. Materials and methods Patient and control groupsWith the approval of the local ethics committee, a prospective study was conducted in our dermatology department clinic. The study comprised 34 patients with vitiligo and 30 age-and sex-matched healthy controls. The patients with vitiligo were newly diagnosed and older than 16 years. The patients with gastrointestinal symptoms or those who had received eradication therapy for HP earlier were excluded from the study. Other exclusion criteria were age under 16 years, pregnancy or lactation, and the use of antibiotics, proton pump inhibitors, or H2 blockers in the 40, 7, and 14 days, respectively, leading up to sample collection. According to the working clinical classification, vitiligo was classified as vitiligo vulgaris, acrofacial, focal, segmental, universal, or mucosal (16).Background/aim: Vitiligo is a common, acquired depigmenting skin disorder. The relationship between Helicobacter pylori (HP) infection and autoimmune dermatological disease has been previously reported. However, the frequency of HP infection in patients with vitiligo has not been reported. In this study, we aimed to investigate the frequency of HP infection with the carbon 14 (C14) urea breath test (UBT) in patients with vitiligo. Materials and methods:This study included 34 patients (18 males and 16 females) with vitiligo and 30 age-and sex-matched healthy controls. HP infection was diagnosed using the C14 UBT (Heliprobe). Statistical analysis was performed using SPSS 19. Results:The frequency of HP infection was 64.7% in the patient group and 33.3% in the control group according to the C14 UBT (chisquare test, P = 0.012). HP infection frequ...

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A review of the worldwide prevalence of vitiligo in children/adolescents and adults

Cited by 430 publications

References 46 publications

Prevalence of vitiligo in Brazil—A population survey

Prevalence of vitiligo in Brazil—A population survey

Targeted NBUVB Phototherapy in Childhood Vitiligo: A Study in 35 Children

Investigation into the frequency of Helicobacter pylori infection with carbon 14 urea breath test in patients with vitiligo

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