A review of three decades of use of the cattle brucellosis rough vaccine Brucella abortus RB51: myths and facts
J. M. Blasco,
E. Moreno,
P. M. Muñoz
et al.
Abstract:Cattle brucellosis is a severe zoonosis of worldwide distribution caused by Brucella abortus and B. melitensis. In some countries with appropriate infrastructure, animal tagging and movement control, eradication was possible through efficient diagnosis and vaccination with B. abortus S19, usually combined with test-and-slaughter (T/S). Although S19 elicits anti-smooth lipopolysaccharide antibodies that may interfere in the differentiation of infected and vaccinated animals (DIVA), this issue is minimized using… Show more
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