2022
DOI: 10.3390/macromol2040037
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A Review of Xyloglucan: Self-Aggregation, Hydrogel Formation, Mucoadhesion and Uses in Medical Devices

Abstract: The present paper reviews the self-aggregation, gel-forming and adsorption properties of xyloglucan (XG), and its main applications as a medical device for wound dressings, mucosal protection and ocular lubrication, as well as its uses as an excipient. XG is a branched polysaccharide composed of a central backbone of D-glucose units linked by β(1→4)-glycosidic bonds, decorated with D-xylose units through α(1→6) glycosidic bonds, and with some D-galactose units anchored to these D-xylose units via β(1→2) bonds.… Show more

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Cited by 9 publications
(1 citation statement)
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“…Aphthae gel is an experimental gel-like SB-MD under study for the treatment of aphthae, stomatitis, and microlesions of the mouth and which, besides the excipients, contains xyloglucan, aloe vera extract, vegetal natural glycerol, and polyvinylpyrrolidone (PVP K30) as active ingredients. All these functional components have hydrating, protective, lenitive, and adhesive properties, as well as film-forming ability (Nair, 1998;Sharma et al, 2014;Esquena-Moret, 2022). Herein, the barrier effect of Aphthae gel was determined by applying the protocol developed.…”
Section: Case Study: Barrier Effect Of Aphthae Gelmentioning
confidence: 99%
“…Aphthae gel is an experimental gel-like SB-MD under study for the treatment of aphthae, stomatitis, and microlesions of the mouth and which, besides the excipients, contains xyloglucan, aloe vera extract, vegetal natural glycerol, and polyvinylpyrrolidone (PVP K30) as active ingredients. All these functional components have hydrating, protective, lenitive, and adhesive properties, as well as film-forming ability (Nair, 1998;Sharma et al, 2014;Esquena-Moret, 2022). Herein, the barrier effect of Aphthae gel was determined by applying the protocol developed.…”
Section: Case Study: Barrier Effect Of Aphthae Gelmentioning
confidence: 99%