A Review on Antiplatelet Drugs and Anticoagulants

Konduru, Jhansi

doi:10.4172/2167-1052.1000003-r

Search citation statements

Order By: Relevance

Paper Sections

Select...

Advantages and Disadvantages Of Case-control Studies1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2016

2022

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

(1 citation statement)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The one final result is the presence or absence of the sickness or whatever criteria have been chosen to select the instances. The most important issues with case-control reports are the familiar ones of confounding variables and bias [56][57][58][59][60].…”

Section: Advantages and Disadvantages Of Case-control Studiesmentioning

confidence: 99%

Epidemiology Concepts for Clinical Trials

Kamarapu¹

2016

Epidemiology (Sunnyvale)

View full text Add to dashboard Cite

show abstract

Section: Advantages and Disadvantages Of Case-control Studiesmentioning

confidence: 99%

Epidemiology Concepts for Clinical Trials

Kamarapu¹

2016

Epidemiology (Sunnyvale)

View full text Add to dashboard Cite

show abstract

New approaches of antiplatelet therapy in the prevention of cardiovascular diseases

Shamilyan

2022

NAMJ

View full text Add to dashboard Cite

Cardiovascular diseases are considered to be the leading cause of mortality in the world.Modifiable and non modifiable risk factors with different mechanisms affect the endothelial cells and lead to development of endothelial dysfunction. Endothelial dysfunction as a cornerstone of cardiovascular diseases’ pathophysiological mechanisms, causes overactivation and over aggregation of platelets resulting in the development of ischemic complications.Though we have huge arsenal of antiplatelet and anticoagulant drugs used for prevention and treatment of ischemic consequences, there is an increase of annual cases of side effects associated with pharmacotherapy.The “gold standard” of antiplatelet therapy - Aspirin gradually loses its role and importance in the primary and secondary prevention, as well as at the treatment of cardiovascular diseases due to the haemorrhage mostly on those patients who are under 70, have diabetes or are in the low and mild risk group of cardiovascular disease.That is why the development of newer and safer substances with possible less hemorrhagic complications has become an important task of modern medicine.In this point of view the plant based agents, containing rich composition of polyphenolic substances, particularly anthocyanins and flavonoids, could serve as potent and promising sources due to their antiplatelet effects, which is conditioned with several action mechanisms.Each action mechanism of polyphenolic substances is directed to the different phases of platelet aggregation. In this paper we have discussed the mechanisms and side effects of antiplatelet drugs with proven activity, the plants as a source for developing new and safe antiplatelet dosage forms and the technological ways to develop optimal drug dosage forms.

show abstract

A Review on Antiplatelet Drugs and Anticoagulants

Cited by 2 publications

References 9 publications

Epidemiology Concepts for Clinical Trials

Epidemiology Concepts for Clinical Trials

New approaches of antiplatelet therapy in the prevention of cardiovascular diseases

Contact Info

Product

Resources

About