A Review on Application of Novel Solid Nanostructures in Drug Delivery

Abstract

Nanotechnology as a multidisciplinary and scientific innovation plays an important role in numerous biomedical applications, such as molecular imaging, biomarkers and biosensors and also drug delivery. A wide range of studies have been conducted on using of nanoparticles for early diagnosis and targeted drug therapy of various diseases. In fact, the small size, customized surface, upgraded solubility, or multi-functionality of nanoparticles enabled them to interact with complex cellular functions in new ways which opened many doors and created new biomedical applications. These studies demonstrated that nanotechnology vehicles can formulate biological products effectively, and this nano-formulated products with a potent ability against different diseases, were represented to have better biocompatibility, bioaccessibility and efficacy, under in vitro and in vivo conditions.

Evaluation of anticancer effects of cerium oxide nanoparticles on mouse fibrosarcoma cell line

“…The utilization of nanomaterials in medicine is expanding (Faraji et al, ). Various nanometals are proposed that have therapeutic properties; some of them are used in cancer studies (Bharali & Mousa, ; Dhar, Gu, Langer, Farokhzad, & Lippard, ; Huang, Jain, El‐Sayed, & El‐Sayed, ; Jain, El‐Sayed, & El‐Sayed, ; Seigneuric et al, ).…”

“…The utilization of nanomaterials in medicine is expanding (Faraji et al, 2018). Various nanometals are proposed that have therapeutic properties; some of them are used in cancer studies (Bharali & Mousa, 2010;Dhar, Gu, Langer, Farokhzad, & Lippard, 2008;Huang, Jain, El-Sayed, & El-Sayed, 2007;; which is vastly applied in nanomedicine; many studies show that it has anticancer and anti-inflammatory properties (Hirst et al, 2009;.…”

Recent Progress in Synthesis and Applications of Zinc Phosphate Nanoparticles: A Review

“…Nanomaterials behave quite unpredictably because surface atoms have profound effects on the overall properties of materials and devices due to their high surface area to volume ratio [5,6]. As a result, nanomaterials have been utilized in the numerous technological applications, such as chemical and biological sensors [7], environmental sensing systems [8], nanoelectronics [9], drug-delivery [10,11], markers of neoplastic disease [12], detection of DNA and protein [13], solar cell [14], nanocoatings [15], sonocatalysts [16] and so on. Among the diverse classes of NPs, inorganic NPs possess special advantages because of their exceptional properties, e.g., hydrophilicity, biocompatibility, higher stability and non-toxic nature [17,18].…”

Synthesis of second-generation self-assembling Gemini Amphiphilic Pseudopeptides

“…The spontaneous self-assembly of molecules leading to well-ordered nano-or micro-structures is a hot topic in supramolecular chemistry with interesting applications in materials science and chemical biology. [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] However, the full understanding of the forces and rules governing the process is still incomplete and requires the study of systematically designed structures with controlled and modular chemical variations. [19][20][21][22][23][24] Among the different varieties of selfassembling molecules reported to date, those showing amphiphilic properties are especially interesting since they can behave in dual manner when media are changed from relatively non-polar organic solvents to buffered aqueous solutions.…”