Lipase-catalyzed organic reactions have been widely practiced in the past
three decades. Especially interesting are insoluble/immobilized forms due to
providing a possibility of facile use and recyclability, thus reducing
process costs, and making the procedure more environmentally friendly.
Carbon-based supports have been extensively exploited for this purpose,
because of neutral and biodegradable nature and thermal and chemical
stability. Their high specific surface area, characteristic surface
morphology and lower mass transfer resistances play a vital role in the
performance of the attached enzyme. This review paper presents an overview
of the main aspects of lipase immobilized on multi-walled carbon nanotubes
(MWCNTs). Moreover, different immobilization strategies to achieve a
biocatalyst with improved performances are discussed. Furthermore, as
lipases are considered to have high commercial worth for synthesis of
valuable organic molecules, the second part of the paper is dedicated to the
overview of the most important industrial sectors in which these
nanobiocatalysts have been used. In specific, applications in biodiesel
production, flavour ester synthesis and racemization are summarized.