A review on chitosan and alginate-based microcapsules: Mechanism and applications in drug delivery systems

Wani, Shahid Ud Din; Ali, Mohammad; Mehdi, Seema; Masoodi, Mubashir Hussain; Zargar, Mohammed Iqbal; Shakeel, Faiyaz

doi:10.1016/j.ijbiomac.2023.125875

Cited by 23 publications

(4 citation statements)

References 112 publications

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“…Nickel ferrite, a soft semiconductor spinel ferrite, has high electrical resistance, and low magnetic saturation 34 , 35 . For biomedical applications, nanoparticles should be coated with biocompatible polymers like chitosan to ensure stability, biodegradability, and non-toxicity in the physiological environment 36 – 38 . Chitosan, a natural polymeric sorbent, has been reported to eliminate anionic dyes from solutions 39 .…”

Section: Introductionmentioning

confidence: 99%

Modeling sunset yellow removal from fruit juice samples by a novel chitosan-nickel ferrite nano sorbent

Shokri,

Shariatifar,

Molaee-Aghaee

et al. 2024

Sci Rep

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Analysis of food additives is highly significant in the food industry and directly related to human health. This investigation into the removal efficiency of sunset yellow as an azo dye in fruit juices using Chitosan-nickel ferrite nanoparticles (Cs@NiFe2O4 NPs). The nanoparticles were synthesized and characterized using various techniques. The effective parameters for removing sunset yellow were optimized using the response surface methodology (RSM) based on the central composite design (CCD). Under the optimum conditions, the highest removal efficiency (94.90%) was obtained for the initial dye concentration of 26.48 mg L−1 at a pH of 3.87, a reaction time of 67.62 min, and a nanoparticle dose of 0.038 g L−1. The pseudo-second-order kinetic model had a better fit for experimental data (R2 = 0.98) than the other kinetic models. The equilibrium adsorption process followed the Freundlich isotherm model with a maximum adsorption capacity of 212.766 mg g−1. The dye removal efficiency achieved for industrial and traditional fruit juice samples (91.75% and 93.24%), respectively, confirmed the method's performance, feasibility, and efficiency. The dye adsorption efficiency showed no significant decrease after five recycling, indicating that the sorbent has suitable stability in practical applications. variousThe synthesized nanoparticles can be suggested as an efficient sorbent to remove the sunset yellow dye from food products.

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Section: Introductionmentioning

confidence: 99%

Modeling sunset yellow removal from fruit juice samples by a novel chitosan-nickel ferrite nano sorbent

Shokri,

Shariatifar,

Molaee-Aghaee

et al. 2024

Sci Rep

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“…Consequently, a range of non-toxic and biodegradable polymers have found extensive use as carrier materials. 15,16 Particularly, poly(l-lysine), heparin, chitosan, dextran, and pullulan have demonstrated significant potential in this regard. Within this group, natural polysaccharides such as starch, chitosan, and cellulose have garnered substantial attention due to their exceptional merits.…”

Section: Introductionmentioning

confidence: 99%

Starch/rhodamine 6G conjugate as a non-cytotoxic, effective, and selective fluorescent chemosensor for detection of Fe³⁺ ion

Alavifar,

Golshan,

Salami Hosseini

et al. 2024

Polymers from Renewable Resources

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Iron is a crucial trace mineral vital for maintaining optimal human health and well-being. Despite being needed in small amounts, its importance cannot be overstated as it plays an important role in various physiological processes. In this research, we have developed a fluorescence probe utilizing starch functionalized with derivatives of rhodamine 6G to efficiently detect Fe3+ ions. This structure forms self-assembled starch/rhodamine 6G (RS0) fluorescent nanoparticles that exhibit strong fluorescence intensity under ultraviolet light. The ability of Fe3+ ions to increase the fluorescence of the RS0 probe enables the effective detection of Fe3+ ions. Importantly, this fluorescence increasing effect is specific to Fe3+ ions and remains unaffected by the presence of other metal ions. MTT assay against SH-SY5Y cells showed that RS0 was rather cytocompatible. Finally, SH-SY5Y cells were used to measure cell uptake and fluorescence imaging performances of RS0 which showed a good ability for live-cell fluorescence imaging.

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“…Prolonged delivery of drugs and therapy for various diseases are the most challenging and sought-after tasks of encapsulation. Although short-term drug dosage is well covered by gel-based microcapsules [4][5][6], long-term sustained drug deposition is not a trivial task, the solution of which requires both minimizing the initial burst release and maintaining the required concentration of the active substance over a long period of time (weeks).…”

Section: Introductionmentioning

confidence: 99%

Template-Free Manufacturing of Defined Structure and Size Polymeric Microparticles

Abdurashitov,

Proshin,

Sukhorukov

2023

Nanomaterials

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Complex-structured polymeric microparticles hold significant promise as an advance in next-generation medicine mostly due to demand from developing targeted drug delivery. However, the conventional methods for producing these microparticles of defined size, shape, and sophisticated composition often face challenges in scalability, reliance on specialized components such as micro-patterned templates, or limited control over particle size distribution and cargo (functional payload) release kinetics. In this study, we introduce a novel and reliably scalable approach for manufacturing microparticles of defined structures and sizes with variable parameters. The concept behind this method involves the deposition of a specific number of polymer layers on a substrate with low surface energy. Each layer can serve as either the carrier for cargo or a programmable shell-former with predefined permeability. Subsequently, this layered structure is precisely cut into desired-size blanks (particle precursors) using a laser. The manufacturing process is completed by applying heat to the substrate, which results in sealing the edges of the blanks. The combination of the high surface tension of the molten polymer and the low surface energy of the substrate enables the formation of discrete particles, each possessing semi-spherical or other designed geometries determined by their internal composition. Such anisotropic microparticles are envisaged to have versatile applications.

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A review on chitosan and alginate-based microcapsules: Mechanism and applications in drug delivery systems

Cited by 23 publications

References 112 publications

Modeling sunset yellow removal from fruit juice samples by a novel chitosan-nickel ferrite nano sorbent

Modeling sunset yellow removal from fruit juice samples by a novel chitosan-nickel ferrite nano sorbent

Starch/rhodamine 6G conjugate as a non-cytotoxic, effective, and selective fluorescent chemosensor for detection of Fe³⁺ ion

Template-Free Manufacturing of Defined Structure and Size Polymeric Microparticles

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A review on chitosan and alginate-based microcapsules: Mechanism and applications in drug delivery systems

Cited by 23 publications

References 112 publications

Modeling sunset yellow removal from fruit juice samples by a novel chitosan-nickel ferrite nano sorbent

Modeling sunset yellow removal from fruit juice samples by a novel chitosan-nickel ferrite nano sorbent

Starch/rhodamine 6G conjugate as a non-cytotoxic, effective, and selective fluorescent chemosensor for detection of Fe3+ ion

Template-Free Manufacturing of Defined Structure and Size Polymeric Microparticles

Contact Info

Product

Resources

About

Starch/rhodamine 6G conjugate as a non-cytotoxic, effective, and selective fluorescent chemosensor for detection of Fe³⁺ ion