A Review on Effect of Solvents on Fluorescent Spectra

Gemeda, Firew

doi:10.9734/csji/2017/32006

Cited by 4 publications

(2 citation statements)

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“…Interactions between the reaction product and solvent molecules affect the shape, intensity, and position of excitation and emission spectra. [21] The effect of the diluting solvent type and the water content in the final reaction medium were also examined as this will be necessary when analyzing large volumes of aqueous samples.…”

Section: Diluting Solventmentioning

confidence: 99%

Highly sensitive spectrofluorimetric method for the determination of the genotoxic methylglyoxal in glycerol‐containing pharmaceuticals and dietary supplements

et al. 2022

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Methylglyoxal (MGO) is a genotoxic α-dicarbonyl compound. Recently, it was found to be formed in glycerol preparations during storage through auto-oxidation. A simple fluorimetric determination of the carcinogenic degradation product of glycerol, MGO, was developed and validated. The proposed method is based on the derivatization of MGO with 4-carbomethoxybenzaldehyde (CMBA) and ammonium acetate to yield a fluorescent imidazole derivative that can be measured at 415 nm after excitation at 322 nm. The optimized conditions were determined to be 0.2 M CMBA, 1.0 M ammonium acetate and a reaction time of 40 min at 90 C using ethanol as diluting solvent. The linear range was 10.0-200.0 ng/ml. Detection and quantification limits were 2.22 and 6.72 ng/ml, respectively. The proposed method was validated according to International Council for Harmonisation (ICH) guidelines and compared with the reported method and no significant difference was found. It was successfully applied for the determination of MGO in six different glycerol-containing pharmaceutical preparations and dietary supplements.

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Section: Diluting Solventmentioning

confidence: 99%

Highly sensitive spectrofluorimetric method for the determination of the genotoxic methylglyoxal in glycerol‐containing pharmaceuticals and dietary supplements

et al. 2022

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“…The fluorescence of a compound can be affected from the solvent used for the fluorophore solution. The solvent effect can be observed as a shift of the spectral maxima (solvatochromic shift), as a change of the intensity of the spectral line or band and as a change of the shape and width of the band [ 26 ]. By increasing the solvent polarity, shifts of the emission spectrum to longer wavelengths (red shifts) are usually observed.…”

Section: Introductionmentioning

confidence: 99%

Review of Fluorescence Spectroscopy in Environmental Quality Applications

2022

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Fluorescence spectroscopy is an optical spectroscopic method that has been applied for the assessment of environmental quality extensively during the last 20 years. Most of the earlier works have used conventional light sources in spectrofluorometers to assess quality. Many recent works have used laser sources of light for the same purpose. The improvement of the energy sources and of the higher resolution spectrometers has led to a tremendous increase in applications. The motivation for the present review study is the increasing use of laser sources in environmental applications. The review is divided in two parts. The fundamental principles of fluorescence spectroscopy are described in the first part. The environmental applications are described in the second part.

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Fluorescence Spectroscopy and Its Applications in Analysing Biomolecular Processes

Alder

2019

Biomolecular and Bioanalytical Techniques

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A Review on Effect of Solvents on Fluorescent Spectra

Cited by 4 publications

References 0 publications

Highly sensitive spectrofluorimetric method for the determination of the genotoxic methylglyoxal in glycerol‐containing pharmaceuticals and dietary supplements

Highly sensitive spectrofluorimetric method for the determination of the genotoxic methylglyoxal in glycerol‐containing pharmaceuticals and dietary supplements

Review of Fluorescence Spectroscopy in Environmental Quality Applications

Fluorescence Spectroscopy and Its Applications in Analysing Biomolecular Processes

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