A Review on Endoscopic Ultrasound-Guided Radiofrequency Ablation (EUS-RFA) of Pancreatic Lesions

Karaisz, Fred; Elkelany, Osama O.; Davies, Ben; Lozanski, Gerard; Krishna, Somashekar G.

doi:10.3390/diagnostics13030536

Cited by 15 publications

(10 citation statements)

References 100 publications

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“…Besides surgery, successful ablative techniques such as radiofrequency ablation (RFA) have also been reported for PM of RCC [ 107 ]. In recent years, EUS-guided RFA has emerged as a promising technique for treating various pancreatic lesions, including pNET, pancreatic cystic neoplasms and PDAC [ 108 , 109 ]. The systematic review by Dhaliwal et al [ 110 ] looking at technical and clinical success rates of EUS-RFA found that of 134 patients treated by RFA, only 4 (3%) had PM, 3 of them from RCC.…”

Section: Discussionmentioning

confidence: 99%

Metastatic Renal Cell Carcinoma to Pancreas: Case Series and Review of the Literature

et al. 2023

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Metastasis to the pancreas represents a small proportion of all pancreatic malignancies. Among primary tumors that metastasize to the pancreas, renal cell carcinoma (RCC) is one of the most common causes of metastatic pancreatic lesions. We herein report a case series of three patients with pancreatic metastasis from RCC. The first is a 54-year-old male with a history of left nephrectomy for RCC, in whom an isthmic pancreatic mass suggestive of a neuroendocrine lesion was found during oncological follow-up. Endoscopic ultrasound (EUS)-guided fine needle biopsy (FNB) identified pancreatic metastasis of RCC and the patient was referred for surgery. The second case is a 61-year-old male, hypertensive, diabetic, with left nephrectomy for RCC six years previously, who complained of weight loss and was found with a hyperenhancing mass in the head of the pancreas and a lesion with a similar pattern in the gallbladder. EUS-FNB from the pancreas proved to be a metastatic pancreatic lesion. Cholecystectomy and treatment with tyrosine kinase inhibitors were recommended. The third case is a 68-year-old dialysis patient referred for evaluation of a pancreatic mass, also confirmed by EUS-FNB, who was started on sunitinib treatment. We report a literature summary on epidemiology and clinical features, diagnosis and differential diagnosis and treatment and outcomes in pancreatic metastasis of RCC.

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Section: Discussionmentioning

confidence: 99%

Metastatic Renal Cell Carcinoma to Pancreas: Case Series and Review of the Literature

et al. 2023

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“…This further helps with tumor lysis. Although RFA is possible via open, laparoscopic, or percutaneous approach, EUS-guided RFA (EUS-RFA) is more advantageous as it is minimally invasive, has high efficacy, offers excellent tumor visualization and localization, provides real-time imaging guidance, and demonstrates an excellent safety profile ( Figure 3 ) [ 61 , 93 , 94 ].…”

Section: Discussionmentioning

confidence: 99%

Role of Therapeutic Endoscopic Ultrasound in Management of Pancreatic Cancer: An Endoscopic Oncologist Perspective

Dahiya,

Chandan,

Ali

et al. 2023

Cancers

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Pancreatic cancer is a highly lethal disease with an aggressive clinical course. Patients with pancreatic cancer are usually asymptomatic until significant progression of their disease. Additionally, there are no effective screening guidelines for pancreatic cancer in the general population. This leads to a delay in diagnosis and treatment, resulting in poor clinical outcomes and low survival rates. Endoscopic Ultrasound (EUS) is an indispensable tool for the diagnosis and staging of pancreatic cancer. In the modern era, with exponential advancements in technology and device innovation, EUS is also being increasingly used in a variety of therapeutic interventions. In the context of pancreatic cancer where therapies are limited due to the advanced stage of the disease at diagnosis, EUS-guided interventions offer new and innovative options. Moreover, due to their minimally invasive nature and ability to provide real-time images for tumor localization and therapy, they are associated with fewer complication rates compared to conventional open and laparoscopic approaches. In this article, we detail the most current and important therapeutic applications of EUS for pancreatic cancer, namely EUS-guided Fine Needle Injections, EUS-guided Radiotherapy, and EUS-guided Ablations. Furthermore, we also discuss the feasibility and safety profile of each intervention in patients with pancreatic cancer to provide gastrointestinal medical oncologists, radiation and surgical oncologists, and therapeutic endoscopists with valuable information to facilitate patient discussions and aid in the complex decision-making process.

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“…are frequently used to coordinate care [24]. On the side of minimally invasive procedures, pancreatic neuroendocrine tumors and precancerous pancreatic cystic lesions can be treated minimally invasive and possibly permanent using endoscopic ablation with ultrasound -guided radiofrequency [25].…”

Section: Discussionmentioning

confidence: 99%

Improve Care in Patients with Pancreatic Pathology

Petre

2023

AJBSR

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BackgroundThe pancreas plays a crucial, fundamental role in the endocrinological control of numerous metabolic processes.Langerhans islands, groups of endocrine cells that produce insulin, glucagon and other hormones in blood flow, play a crucial role in regulating glucose homeostasis [1]. In 2020, about 47,000 cases of worldwide pancreatic cancer were anticipated (Cancer.net).Thus, the sixth most common cause of the deaths caused by global cancer is given by pancreatic cancer. It has also been observed that more developed countries suffer significantly more than the other countries [2].The top 10 countries with pancreatic cancer are Hungary,

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A Review on Endoscopic Ultrasound-Guided Radiofrequency Ablation (EUS-RFA) of Pancreatic Lesions

Cited by 15 publications

References 100 publications

Metastatic Renal Cell Carcinoma to Pancreas: Case Series and Review of the Literature

Metastatic Renal Cell Carcinoma to Pancreas: Case Series and Review of the Literature

Role of Therapeutic Endoscopic Ultrasound in Management of Pancreatic Cancer: An Endoscopic Oncologist Perspective

Improve Care in Patients with Pancreatic Pathology

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