A Review on Extraction of Bioactive Compounds from Moringa oleifera Leaves: Their Principle, Advantages, and Disadvantages

Abstract

Moringa oleifera, belongs to the Moringaceae family, is an indigenous plant and native to the North India region. It has been used for centuries as traditional medicine and nutritional supplement. Moringa olefeira leaves contain high phenolics and flavonoid compounds as major constituents such as kaempferol, quercetin, caffeoylquinic acid, coumaroylquinic acid, and feruloylquinic acid. The extraction techniques play a critical role in the extraction outcome such as crude extracts yield, type and quantity of compound extracted. To date, there is a wide range of technologies for crude plant extraction such as ultrasoundassisted extraction, microwave-assisted extraction Soxhlet extraction, and dipping (maceration) technique. These extraction techniques employ various types of solvent which could enhance the efficiency of extraction and quality of the compound extracted. Hence, this review aims to describe and compare the conventional and novel extraction techniques methods of Moringa oleifera leaves based on the total phenolics content, flavonoid content, and antioxidant activity. The difference based on the extraction process principle, advantages, and disadvantages were further evaluated to show the suitability, environmentally friendly, the economic feasibility of the various extraction methods. From this review, ultrasound-assisted extraction (UAE) and microwave-assisted extraction (MAE) have minimized the processing time, which is useful for extracting thermolabile compounds, such as phenol compounds. In conclusion, novel extraction techniques could be effectively enhancing the total phenolic compound, flavonoid content, and antioxidant activities of crude extracts, which provides a theoretical basis for upgrading to alarge-scale applicationin the future.

Moringa oleifera Leaf Ethanol Extract Inhibits Toxoplasma gondii Tachyzoites Replication

“…Factors influencing the maceration process results are temperature, solvent types and concentration, duration, and other factors. 22 The extraction of M. oleifera leaves using methanol as a solvent with 72 hours of maceration showed positive saponin results on the phytochemical screening. 7 Positive saponin results were also obtained in the extraction using ethanol as the solvent with a maceration time of 72 hours.…”

Moringa oleifera Seed Cake: A Review on the Current Status of Green Nanoparticle Synthesis

“…A high-yield purified protein extract from M. oleifera seeds was obtained by ultrasoundassisted extraction, in which ultrasound power and pH were the two most influential experimental parameters impacting protein yield and quality [55]. Other factors such as temperature, time, and cost also impact the biocomponents extracted from M. oleifera and should be carefully optimized, depending on the specific requirements of the intended application [56].…”

“…sisted extraction, in which ultrasound power and pH were the two most imental parameters impacting protein yield and quality [55]. Other fac perature, time, and cost also impact the biocomponents extracted fro should be carefully optimized, depending on the specific requirement application [56].…”