A review on factors influencing bioaccessibility and bioefficacy of carotenoids

Priyadarshani, A.M.B.

doi:10.1080/10408398.2015.1023431

Cited by 79 publications

(39 citation statements)

References 63 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Height was not correlated with CRS. Explanations for this association with body composition include that carotenoids are fat soluble and the concentration in body tissues will depend on both the amount (dose) ingested and absorbed [17] and also the volume of distribution. Larger people will have more absolute fat mass and higher body fat percentage.…”

Section: Discussionmentioning

confidence: 99%

Determinants and Suitability of Carotenoid Reflection Score as a Measure of Carotenoid Status

et al. 2020

View full text Add to dashboard Cite

Carotenoids, orange-coloured pigments found in vegetables, fruit, eggs and dairy foods, act as antioxidants and vitamin A precursors in the human body. Skin carotenoid concentration is a biomarker of vegetable and fruit intake. The aim was to identify determinants of skin carotenoid concentration by measuring “Veggie Meter™” carotenoid reflection spectroscopy scores (CRS) from the fingertip of adults with a range of ages, ethnicity and body size. Frequencies of daily intake of vegetables and fruit and weekly intake of pumpkin and carrot, dark green leafy vegetables (DGLV), eggs (yolk), and dairy were determined from a self-completed food-frequency-questionnaire. A total of 571 (324 Women, 247 Men) adults, aged 16 to 85 years, completed measurements. The CRS ranged from 83 to 769, with a median of 327. Women and men did not score differently. For all participants there were negative correlations of CRS with weight (r = −0.312) and BMI (r = −0.338) and positive correlations with weekly intakes of DGLV (r = 0.242) and carrots and pumpkin (r = 0.202). Based on a review of health outcomes associated with plasma carotenoids, 82% of the participants in the current study are at moderate risk, or more, of negative health outcomes. Determinants of carotenoid status were body size, intake of DGLV, carrots and pumpkin, and ethnicity.

show abstract

Section: Discussionmentioning

confidence: 99%

Determinants and Suitability of Carotenoid Reflection Score as a Measure of Carotenoid Status

et al. 2020

View full text Add to dashboard Cite

show abstract

“…The absorption of carotenoids has many parallels to that of lipids . For their absorption, carotenoids must be released from the food matrix . The carotenoids are then incorporated into mixed micelles, which consist primarily of free fatty acids, bile salts, cholesterol, phospholipids, and other lipids .…”

Section: Absorption Bioavailability and Tissue Distributionmentioning

confidence: 99%

Canthaxanthin: From molecule to function

Esatbeyoglu¹,

Rimbach²

2016

Molecular Nutrition Food Res

View full text Add to dashboard Cite

The aim of this review is to summarize the relevant literature about the use of canthaxanthin in food science and nutrition research. Canthaxanthin is a red-orange carotenoid that belongs to the xanthophyll group. This naturally occurring pigment is present in bacteria, algae and some fungi. Canthaxanthin is also responsible for the color of flamingo feathers, koi carp skin and crustacean shells. Canthaxanthin is widely used in poultry (broiler, laying hens) as a feed additive. Canthaxanthin can be obtained by total synthesis. The canthaxanthin-mediated color of foods is an important quality criterion for consumers. Recently, the potential health-promoting effects of canthaxanthin have been discussed. Canthaxanthin enrichment of LDL has the potential to protect cholesterol from oxidation. In addition to its free radical scavenging and antioxidant properties (e.g., the induction of catalase and superoxide dismutase), canthaxanthin's immunomodulatory activity (e.g., enhancing the proliferation and function of immune competent cells) and its important role in gap junction communication (e.g., induction of the transmembrane protein connexin 43) have been reported. Many studies regarding the potential health benefits of canthaxanthin have been conducted in vitro and should be validated in appropriate in vivo models.

show abstract

“…This is supported by research demonstrating competitive inhibition between carotenoids [33], though the details of this physiological mechanism are still being researched. Carotenoid bioavailability is a complex, multifactorial process influenced by the quantity and species of carotenoids consumed, whether carotenoids are consumed with fat and/or fiber [34], the presence of key vitamins and nutrients that act as co-factors [35], serum HDL levels, body fat percentage, and endogenous carotenoid stores [36].…”

Section: Discussionmentioning

confidence: 99%

Restoration of Central Macular Pigment Dip with Dietary RR Zeaxanthin Supplementation in Patients with AMD

Richer¹

2017

AOVS

View full text Add to dashboard Cite

Objective: Low macular pigment optical density (MPOD) is a major risk factor for age-related macular degeneration (AMD). This paper investigates the impact of 8 mg dietary RR zeaxanthin (Z) supplementation on MPOD distribution and the associated effect on macular scotomas in patients with a central foveal dip in their macular pigment spatial profile.Methods: This is a retrospective review of The Zeaxanthin and Visual Function RCT (FDA IND 78, 973) with respect to the relation between low levels of MPOD and increased risk of age-related macular degeneration (AMD). We retrospectively examine the effect of daily supplementation of 8 mg of dietary Z on n=4 patients having a baseline central foveal dip in their MPOD distribution. The testing modalities used were a 7⁰ 3D specular reflectance and the associated kinetic 20° macular visual fields.Results: Over a 12-month period, all four patients showed a progressive increase in central peak restoration with related kinetic and/or Amsler grid visual field data. Conclusion:The initial results demonstrate marked improvement in macular pigment architecture and overall visual function after 12 months of Z supplementation. These results warrant a prospective clinical trial with a larger number of subjects to investigate the role of Z in central dip amelioration.

show abstract

A review on factors influencing bioaccessibility and bioefficacy of carotenoids

Cited by 79 publications

References 63 publications

Determinants and Suitability of Carotenoid Reflection Score as a Measure of Carotenoid Status

Determinants and Suitability of Carotenoid Reflection Score as a Measure of Carotenoid Status

Canthaxanthin: From molecule to function

Restoration of Central Macular Pigment Dip with Dietary RR Zeaxanthin Supplementation in Patients with AMD

Contact Info

Product

Resources

About