A Review on Formulation Development and Evaluation of Novel Topical Emulgel (An Overview)

Abstract

Over the last decade the treatment of illness has been accomplished by administering drug to human body via various routes namely oral, sublingual, rectal, parental etc. Many advantages of gels a major limitation is in the delivery of hydrophobic drugs. So to overcome this limitation an emulsion based approach is being used so that even a hydrophobic therapeutic moiety can enjoy the unique properties of gels. The topical drug delivery system is generally used where these systems of drug administration fails or in local skin infection like fungal infection. Topical drug delivery can be defined as the application of a drug containing formulation to the skin to directly treat cutaneous disorder. The combination of hydrophilic cornified cells in hydrophobic intercellular material provides a barrier to both hydrophilic and hydrophobic substances. Within the major group of semisolid preparations, the use of transparent gels has expanded both in cosmetics and in pharmaceutical preparations. Polymer can function as emulsifiers and thickeners because the gelling capacity of these compounds allows the formulation of stable emulsions and creams by decreasing surface and interfacial tension and at the same time increasing the viscosity of the aqueous phase. These Emulgel are having major advantages on novel vesicular systems as well as on conventional systems in various aspects. Various permeation enhancers can potentiate the effect, so Emulgel can be used as better topical drug delivery systems over present systems.

Chemical composition and sensory evaluation of potato-sprouted Africa yam beans based complementary food fortified with palm weevil

“…Legumes on the other hand, are important sources of proteins, carbohydrates, dietary fiber and minerals and are useful sources of B vitamins consumed worldwide (Martin et al, 2010) [25] . Legumes are known to contain lysine in a quantity that exceeds the requirements for humans but with low content of sulphur containing amino acids (Mishra et al, 2014) [28] . Due to increasing cases of malnutrition in most developing and under-developed countries as a result of difficulties in providing sufficient food, most especially protein (Aylward and Morgans, 1995) [9] , insects are being presented as an attractive alternative protein source as they are natural foods of many vertebrates, human inclusive (DeFoliart, 1999) [12] .…”