A review on metal-oxide based trace ammonia sensor for detection of renal disease by exhaled breath analysis

Shetty, Shrushti S.; Jayarama, A.; Bhat, Shashidhara; Satyanarayan,; Karunasagar, Iddya; Pinto, Richard S.

doi:10.1016/j.matpr.2021.12.411

Cited by 15 publications

(5 citation statements)

References 62 publications

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“…In addition, NH 3 is also present in the exhaled breath of kidney disease patients. By detecting the exhaled NH 3 , it is possible to achieve an early diagnosis of kidney disease [4][5][6]. Therefore, the NH 3 sensor has received widespread attention and rapid development in recent years.…”

Section: Introductionmentioning

confidence: 99%

Pd-Decorated ZnO Hexagonal Microdiscs for NH3 Sensor

Li,

Zhang,

et al. 2024

Chemosensors

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The NH3 sensor is of great significance in preventing NH3 leakage and ensuring life safety. In this work, the Pd-decorated ZnO hexagonal microdiscs are synthesized using hydrothermal and annealing processes, and the gas sensor is fabricated based on Pd-decorated ZnO hexagonal microdiscs. The gas-sensing test results show that the Pd-ZnO gas sensor has a good response to NH3 gas. Specifically, it has a good linear response within 0.5–50 ppm NH3 at the optimal operating temperature of 230 °C. In addition, the Pd-ZnO gas sensor exhibits good repeatability, short response time (23.2 s) and good humidity resistance (10–90% relative humidity). This work provides a useful reference for developing an NH3 sensor.

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Section: Introductionmentioning

confidence: 99%

Pd-Decorated ZnO Hexagonal Microdiscs for NH3 Sensor

Li,

Zhang,

et al. 2024

Chemosensors

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“…Moreover, it is being increasingly used as a source of green hydrogen [ 8 ] and an important biomarker in disease monitoring. [ 9 ] Despite its widespread use, NH 3 is highly toxic, corrosive, and damaging to human health and the environment. Short‐term (10–15 min) exposure limits to NH 3 are typically set at 35 parts per million (ppm) while longer (8–10 h) limits are set at 25 ppm.…”

Section: Introductionmentioning

confidence: 99%

Molecular Engineering of Silicon Phthalocyanine to Improve the Charge Transport and Ammonia Sensing Properties of Organic Heterojunction Gas Sensors

Moorthy

King

Kumar

et al. 2022

Advanced Sensor Research

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Novel organic heterostructures fabricated with a bilayer consisting of an axially substituted silicon phthalocyanine (R 2 -SiPc) derivative and lutetium bis-phthalocyanine (LuPc 2 ) are investigated for their ammonia sensing properties. Surface and microstructure characterization of the heterostructure films reveal either compact or highly porous surface topography in (345F) 2 -SiPc and Cl 2 -SiPc-based heterostructures, while electrical characterization reveals a strong influence of the axial substituent in R 2 -SiPc on NH 3 sensing capabilities. Electrical characterization further demonstrates an apparent energy barrier for interfacial charge transport, which is higher in the (345F) 2 -SiPc/LuPc 2 heterojunction device. In-depth charge transport studies by impedance spectroscopy further reveal a resistive interface in (345F) 2 -SiPc/LuPc 2 and faster bulk and interfacial charge transport in Cl 2 -SiPc/LuPc 2 heterojunction devices. Different interfacial charge transport capabilities and surface topographies affect NH 3 sensing properties of the two heterojunction devices, in which (345F) 2 -SiPc/LuPc 2 reveals a fast and non-linear response with a limit of detection (LOD) of 310 ppb, while Cl 2 -SiPc/LuPc 2 exhibits a slow, and linear response to NH 3 with LOD of 100 ppb. Finally, different metrological parameters of the two sensors are correlated to the respective gas-material interactions, in which adsorption and diffusion regimes are modulated by the surface topography and hydrophobicity of the sensing layer.

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“…Depending on the type of metal oxide and dopant used, a wide range of gases can be detected, but the downsides of the system are the high operating temperature and narrow range of detectable analytes. MOx based chemical sensors are used in the detection of obnoxious gases for the purpose of environmental monitoring SO 2 [37,[81][82][83], NO x [84][85][86], NH 3 [87,88], H 2 S [89], CO [90,91] hydrocarbons [detection of oil spills], and VOCs [volatile organic compounds]. Such sensors have been light-powered and realized on flexible substrates for the detection of NO 2 by ultrathin heterostructure configuration (see Figure 6).…”

Section: State Of the Art Of Chemiresistive Sensorsmentioning

confidence: 99%

State of the Art of Chemosensors in a Biomedical Context

et al. 2022

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Healthcare is undergoing large transformations, and it is imperative to leverage new technologies to support the advent of personalized medicine and disease prevention. It is now well accepted that the levels of certain biological molecules found in blood and other bodily fluids, as well as in exhaled breath, are an indication of the onset of many human diseases and reflect the health status of the person. Blood, urine, sweat, or saliva biomarkers can therefore serve in early diagnosis of diseases such as cancer, but also in monitoring disease progression, detecting metabolic disfunctions, and predicting response to a given therapy. For most point-of-care sensors, the requirement that patients themselves can use and apply them is crucial not only regarding the diagnostic part, but also at the sample collection level. This has stimulated the development of such diagnostic approaches for the non-invasive analysis of disease-relevant analytes. Considering these timely efforts, this review article focuses on novel, sensitive, and selective sensing systems for the detection of different endogenous target biomarkers in bodily fluids as well as in exhaled breath, which are associated with human diseases.

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A review on metal-oxide based trace ammonia sensor for detection of renal disease by exhaled breath analysis

Cited by 15 publications

References 62 publications

Pd-Decorated ZnO Hexagonal Microdiscs for NH3 Sensor

Pd-Decorated ZnO Hexagonal Microdiscs for NH3 Sensor

Molecular Engineering of Silicon Phthalocyanine to Improve the Charge Transport and Ammonia Sensing Properties of Organic Heterojunction Gas Sensors

State of the Art of Chemosensors in a Biomedical Context

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