A review on recent developments in optical and electrochemical aptamer-based assays for mycotoxins using advanced nanomaterials

Goud, K. Yugender; Reddy, K. Koteshwara; Satyanarayana, M.; Kummari, Shekher; Gobi, K. Vengatajalabathy

doi:10.1007/s00604-019-4034-0

Cited by 112 publications

(52 citation statements)

References 157 publications

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“…Functional nucleic acids, coupled with novel transducers and nanoprobes, offer a variety of biosensors for foodborne contaminant detection [460][461][462]. These biosensors have achieved rapid and sensitive detection of pathogens ( Figure 19(a)) [463], mycotoxins (Figure 19(b)) [464,465], allergens [468], pesticides [467], heavy metal ions [468] and illegal additives [469], with a great application potential in POCT. In the future, the development of Figure 18 Nucleic acid-based environmental analysis.…”

Section: Food Analysismentioning

confidence: 99%

Nucleic Acids Analysis

et al. 2020

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In recent years, multi-modal entity linking (MEL) has garnered increasing attention in the research community due to its significance in numerous multi-modal applications. Video, as a popular means of information transmission, has become prevalent in people's daily lives. However, most existing MEL methods primarily focus on linking textual and visual mentions or offline videos's mentions to entities in multi-modal knowledge bases, with limited efforts devoted to linking mentions within online video content. In this paper, we propose a task called Online Video Entity Linking (OVEL), aiming to establish connections between mentions in online videos and a knowledge base with high accuracy and timeliness. To facilitate the research works of OVEL, we specifically concentrate on live delivery scenarios and construct a live delivery entity linking dataset called LIVE. Besides, we propose an evaluation metric that considers timelessness, robustness, and accuracy. Furthermore, to effectively handle OVEL task, we leverage a memory block managed by a Large Language Model and retrieve entity candidates from the knowledge base to augment LLM performance on memory management. The experimental results prove the effectiveness and efficiency of our method.

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Section: Food Analysismentioning

confidence: 99%

Nucleic Acids Analysis

et al. 2020

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“…Major mycotoxins include aflatoxins, gliotoxin, citrinin, ergot alkaloids, fumonisins, ochratoxin, and patulin. Although important, the details of mycotoxins and their detection have been reviewed extensively [161][162][163] and are beyond the scope of this review, which focusses on the detection of fungal cells. Their potential role as biomarkers of infection would also be limited by the fact that many are only produced under very specific growth conditions.…”

Section: Mycotoxinsmentioning

confidence: 99%

Biosensors and Diagnostics for Fungal Detection

Hussain

Malavia

Johnson

et al. 2020

JoF

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Early detection is critical to the successful treatment of life-threatening infections caused by fungal pathogens, as late diagnosis of systemic infection almost always equates with a poor prognosis. The field of fungal diagnostics has some tests that are relatively simple, rapid to perform and are potentially suitable at the point of care. However, there are also more complex high-technology methodologies that offer new opportunities regarding the scale and precision of fungal diagnosis, but may be more limited in their portability and affordability. Future developments in this field are increasingly incorporating new technologies provided by the use of new format biosensors. This overview provides a critical review of current fungal diagnostics and the development of new biophysical technologies that are being applied for selective new sensitive fungal biosensors to augment traditional diagnostic methodologies.

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“…alternative to the enzyme labels (Sun, Zhao, Feng, & Xie, 2018), etc. (Goud et al, 2018(Goud et al, , 2019Rhouati et al, 2017). Previous reviews (Goud et al, 2019;Rhouati et al, 2017)…”

Section: Nanomaterials-based Aptasensorsmentioning

confidence: 99%

Recent advances on emerging nanomaterials for controlling the mycotoxin contamination: From detection to elimination

Zhang

et al. 2020

Food Frontiers

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Mycotoxins, a toxic secondary metabolite, unpredictably, and unavoidably occur in foods and feeds, leading to adverse health impacts and enormous economic losses in the agriculture industry. Moreover, mycotoxin contamination has been a great threat for the public health and agriculture economy development worldwide. Therefore, the control of the mycotoxin contamination is of great importance and has caused rising concern worldwide. Recently, emerging nanomaterials have been promisingly applied in the control of mycotoxin contamination and have obtained many achievements. In this review, first of all, the type, occurrence, and toxicity of mycotoxins are simply discussed. Then, attentions are focused on the applications of emerging nanomaterials to controlling the mycotoxin contamination, including mycotoxin assay, the inhibition of mycotoxin production, the adsorption of mycotoxins, and mycotoxin elimination. In the end, the future opportunities and challenges on the toxicity, occurrence, and control of mycotoxins are tentatively put forward.

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A review on recent developments in optical and electrochemical aptamer-based assays for mycotoxins using advanced nanomaterials

Cited by 112 publications

References 157 publications

Nucleic Acids Analysis

Nucleic Acids Analysis

Biosensors and Diagnostics for Fungal Detection

Recent advances on emerging nanomaterials for controlling the mycotoxin contamination: From detection to elimination

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