A Review on Relevance of Herbal Medications for Psychiatric Patients

Aswathi, T; Venkateswaramurthy, N.; R, Sambath Kumar.

doi:10.5958/0974-360x.2019.00531.6

Cited by 5 publications

(1 citation statement)

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“…19 The result also suggested that care should be taken in the use of standard drugs along with herbal preparations since such combinations could produce different results with different drugs. 26 In the forced swim test, a significant dose dependent decrease in the immobility time of the animals (corresponding to the increase swimming or struggling time), administered A. muricata stem bark extract was observed compared to the control group as shown in Figure 5. The animals administered the extract exhibited increased swimming (struggling) tendencies.…”

Section: Resultsmentioning

confidence: 92%

Annona muricata L., Stem-Bark Exhibit Antidepressant-Like Activity in SpragueDawley Rats

2023

TJNPR

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Annona muricata L. (Annonaceae) is widely used in the Amazon and Carribean in natural medicine as an antiparasitic, insecticidal, sedative and as an astringent for diarrhea among others. In Nigeria however, Annona muricata is among the under-utilized species of plants. This study investigated the antidepressant and ambulatory effect of A. muricata, using the open field test and forced swim tests on Sprague-Dawley rats administered ethanol stem-bark extracts of the Nigerian grown species. Rats were administered A. muricata stem-bark extract (50, 150 and 300mg/kg) alone and in combination with the drugs imipramine and sertraline (10mg/kg), respectively for 14 days. The administration of the extract was observed to cause a significant reduction in the swimming time and immobility time of the rats in the forced swim test. The ambulatory behavior of the rats was observed to decrease when the extract (150 and 300mg/kg) was administered alone to the rats while a much further decrease was observed in the explorative tendencies of the rats when the extract was combined with the imipramine and sertraline. The results suggested that the ethanol stem-bark extract of A.muricata, possess sedative and antidepressant effects

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Section: Resultsmentioning

confidence: 92%

Annona muricata L., Stem-Bark Exhibit Antidepressant-Like Activity in SpragueDawley Rats

2023

TJNPR

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Effect of Ultra-diluted Medicines in Depression and Anxiety: A Narrative Review

Bhat

Bakthavatchalam

Krishnan³

et al. 2021

RJPT

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Background: Generalized anxiety disorder (GAD) and depression are the common mental health diseases affecting millions of people globally. The conventional treatment with medications causes a lot of adverse effects leading patients to seek relief from alternative systems of medicine. The alternative mode of treatment, Homeopathy, uses ultra-diluted drugs to treat GAD and Depression. Objective: This review is to narrate and assess the effectiveness of homeopathy in anxiety and depressive disorders. Also, the related animal studies and in-vitro studies have been evaluated. Methods: The search used combinations of Medical Subject Heading terms ultra-diluted, anxiety, and depression. Lists of articles under references were reviewed to identify additional studies. Results: Studies suggest that ultra diluted, dynamised medicines are used by homeopathic practitioners to treat anxiety and depression. Homeopathic physicians prescribe individualized drugs after a detailed case taking. These have a favorable effect on the patients compared to control and also to conventional medicines. In- vivo studies show encouraging results as ultra- diluted drugs act as anxiolytics without altering the motor abilities of the animal models. In-vitro studies are lacking to reach a decisive inference. Conclusion: Although there are enough preliminary studies establishing proof of the effect of homeopathy in mental health ailments, further exploration is essential and ought to embrace well premeditated controlled studies with sufficient sums of participants.

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Parthenium-Turmeric ointment: A novel approach for excision wound healing on rabbits

Dutta

Ash²,

Roy³

et al. 2022

RJPT

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Traditional phytomedicines owing to their affordable price and fewer side effects over synthetic preparations may have a wide range of applications in primary health care system. However, there was no scientific report documented so far on the excision wound healing activity of Parthenium hysterophorus-Turmeric ethanolic extract on rabbits. The present study deals with the formulation and evaluation of Parthenium hysterophorus-Turmeric ointment in definite ratio. The four batches were examined for hemocompatibility study and characterised for physical appearance, pH, rheological behaviour, in-vitro drug diffusion pattern, skin irritation excision wound healing and stability study. All the hemocompatible herbal formulations were found to possess satisfactory organoleptic properties and applicability parameters. An inverse relationship was observed between viscosity and % spreadability of ointments. Non-Fickian diffusion based controlled drug release was observed for all these topical preparations. Excision wound healing activity was assessed on the basis of % wound contraction, duration of epithelisation and tensile strength. PHTO1 (ethanolic extract of Parthenium hysterophorus: Turmeric-3:2) showed greater (1.10-1.34 times) wound healing activity compared to only Parthenium extract containing ointment (PHO1). Tissue debride effect was also observed after 7th day of applications of each formulation. All the prepared Parthenium-Turmeric formulations were found to be stable suggesting elaborative research to confirm the pharmacologically active constituent responsible for excision wound healing activity.

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A Review on Relevance of Herbal Medications for Psychiatric Patients

Cited by 5 publications

References 0 publications

Annona muricata L., Stem-Bark Exhibit Antidepressant-Like Activity in SpragueDawley Rats

Annona muricata L., Stem-Bark Exhibit Antidepressant-Like Activity in SpragueDawley Rats

Effect of Ultra-diluted Medicines in Depression and Anxiety: A Narrative Review

Parthenium-Turmeric ointment: A novel approach for excision wound healing on rabbits

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