To avoid hunger and meet the needs of the increasing global population (expected to be 9.76 billion by 2050), it is very necessary to increase agricultural production. Since 1960, the application of pesticides has been one of the factors that have improved agricultural production. Pesticides protect the crops from insects, fungi, bacteria, and competing weeds. The pesticide also protects the stored agricultural products from rodents and other pests. Out of more than 10,000 synthetic chemical compounds used as pesticides nowadays, about 2000 active ingredients in 60 classes of chemicals are used as pesticides globally. Pesticides are also used to protect citizens from vector-borne diseases. In 2021, about 4.2 million metric tonnes of pesticides will have been used as agrochemicals globally. Some of the applied pesticides that are toxic to humans persist for a very long time in the environment as they cannot be easily degraded or bio-accumulated. The residues of the pesticides or related daughter products are present in all the compartments of aquatic and terrestrial environments (soil, groundwater, surface water, food chain, sea products, vegetables, fruits, animal milk, and breast milk). When humans and other animal's uptake pesticide-contaminated food and water, the pesticides are bio accumulated in humans and animals. The exposure of humans and animals to pesticides may cause short-term effects such as headaches, nausea, asthma, sore throat, eye irritation, skin irritation, diarrhoea, pharyngitis, nasal irritation, sinusitis, contact dermatitis, or long-term effects related to growth, neurotoxicity, endocrine disruption, liver and kidney damage, breast, prostate, brain, liver cancer, and reproductive effects (sperm abnormalities, infertility, birth defects, abortion). For a better life, it is How pesticides… O.P. Bansal.