A review on the ethnopharmacology, phytochemistry and pharmacology of Polygonum hydropiper Linn.

Abstract

Objectives Polygonum hydropiper is a herb with worldwide distribution, having tremendous value as traditional medicine among different communities. It is used to cure many kinds of ailments such as gynaecological disorders, ulcer, anxiety, pain, cancer, etc. The present review gives emphasis on a thorough and updated study of the botanical description and taxonomy, distribution, habitat, ethnopharmacology, phytochemical constituents, pharmacological activities and toxicological aspects of P. hydropiper. Methods The information included in this review was collected from different scientific databases like PubMed, ScienceDirect, Google Scholar, etc. In addition to the botanical description and taxonomy, lots of ethnomedicinal use of the water-pepper plant could be found. Result A good number of compounds belonging to the categories like alkaloids, carbohydrates, flavonoids, etc. were confirmed to be present in the plant. Moreover, in different studies, this plant was found to possess activities like anti-Alzheimer, antibacterial, antidementia, antifertility, neuropharmacological, sedative, anxiolytic, thrombolytic and membrane-stabilizing activity, etc. with minimal toxicity. Conclusion These properties may be directly related to its possession of a large number of bioactive molecules of different categories. Based on these properties, isolation of responsible compound(s), evaluation of molecular mechanisms of their action and clinical trials are recommended.

The genus Polygonum: An updated comprehensive review of its ethnomedicinal, phytochemical, pharmacological activities, toxicology, and phytopharmaceutical formulation

“…The distinctive properties of essential oils are attributed to their highly complicated mixes of monoterpenes and sesquiterpenes, which also contain biogenetically linked phenols, alcohols, aldehydes, ethers, carbohydrates, and ketones [ 74 ]. The essential oil compositions of many species in the Polygonum genus, including P. hydropiper [ 75 ] and P . bistorta [ 11 ], have been investigated.…”

Antioxidant Activity of Total Flavonoids from Persicaria hydropiper (L.) Spach and Their Bacteriostatic Effect on Pathogenic Bacteria of Broiler Origin

“…The single-factor tests were carried out based on the fixed solid-liquid ratio of 1:20, heating reflux time of 60 min, heating reflux temperature of 60 • C, ethanol concentration of 50%, and extraction times of 3 to investigate the solid-liquid ratio (g/mL) (1:10, 1:15, 1:20, 1:25, 1:30), heating reflux time (min) (30,60,90,120,150), heating reflux temperature ( • C) (40,50,60,70,80), ethanol concentration (%) (30,40,50,60,70), and extraction times (times) (1,2,3,4) on the extraction yield of TFs-Ph.…”

“…Persicaria hydropiper (L.) Spach, a traditional Chinese herbal medicine, is an annual herb of the genus Polygonum in the family Polygonaceae [1]. It has the effects of detumescence, clearing away heat and toxic materials, activating blood and dissolving stasis, and treating rheumatic pain [2], and flavonoids are the main active components [3,4].…”

Potential Extracts of Melastomataceae Species from Mount Merapi National Park as Sunprotection Material with Antioxidation and Antiglycation Activities

“…30 Aminoguanidine is a well-known synthetic compound which can block the formation of AGEs by interacting with amadori-derived products. 31 Therefore, aminoguanidine was used as a positive control material in the antiglycation BSA-glucose assay. C. hirta extract had higher anti-glycation activity than M. affine extract (Table 5).…”