A Review on the Genetic, Environmental, and Lifestyle Aspects of the Early-Life Origins of Cardiovascular Disease

Kelishadi, Roya; Poursafa, Parinaz

doi:10.1016/j.cppeds.2013.12.005

Cited by 137 publications

(134 citation statements)

References 272 publications

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“…The present study found similar obesity rates between 1.5 and 5 years of age in LBW and NBW children. However, further follow-up to adolescence and adulthood is neces-sary, given that obesity and its related disorders seem to appear later in life [11] [12] [19] [20].…”

Section: Discussionmentioning

confidence: 99%

Underweight and Obesity in Low Birth Weight Children in Early Infancy in Japan

Kato¹,

Kubota²,

Saito³

et al. 2015

FNS

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Introduction: Although there are several reports on the prevalence of underweight or obesity in low birth weight (LBW, <2.5 kg) children, there are few longitudinal studies from birth to early infancy. Methods: We enrolled 177 (93 boys) LBW and 2485 (1267 boys) normal birth weight (NBW, ≥2.5 and <4.0 kg) children. Height and weight data at birth and at 1.5, 3.5, and 5 years were obtained from mother-health child records. Underweight and obesity were defined as <5 th percentile and ≥90 th percentile of the body mass index (BMI), respectively, based on reference values for Japanese children. Results: LBW children had accelerated growth from birth to age 3.5 years, but at Age 5, both sexes had significantly lesser height and weight z-scores, with notably lesser BMI percentile scores for girls, compared with NBW children. The prevalence of underweight was significantly higher in the LBW children throughout the study period. There were no significant differences in the prevalence of obesity between the two groups, except for at birth. Multiple regression analysis revealed that small-for-gestational age was associated with underweight at Age 5 years. Conclusions: This study indicates that, up to Age 5, underweight is a more serious problem than obesity in LBW children. Our results suggest that careful observation of growth from early infancy is necessary to prevent the occurrence of underweight in early infancy.

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Section: Discussionmentioning

confidence: 99%

Underweight and Obesity in Low Birth Weight Children in Early Infancy in Japan

Kato¹,

Kubota²,

Saito³

et al. 2015

FNS

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“…[3] Kalıtım, cinsiyet, etnik köken, sedanter yaşam biçimi ve fiziksel aktivitenin azlığı gibi gerek genetik, gerekse çevresel birçok faktör obeziteden sorumludur. [4,7] Özellikle beslenme alışkanlığının hazır yiyecek türüne kaymasının, ayaküstü yenilen hamburger, patates kızartması gibi yiyeceklerin fazla tüketilmesinin obezite gelişiminde etkisi fazladır. [8] Sonuçta obezitenin önemli bir risk faktörü olduğu hipertansiyon, koroner kalp hastalıkları, diyabet gibi birçok kronik hastalık açısından yetişkinler kadar, çocuklar da önemli risk altındadır.…”

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Obesity frequency in school children and related risk factors

Savaşhan¹

2015

tahd

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Obesity frequency in school children and related risk factors ÖzetAmaç: Çocukluk çağı obezitesi ileride erişkin obezitesi olarak devam etmesi, komplikasyonlara bağlı morbidite ve mortalitede ciddi artışlar yaşanması ve en önemlisi de çoğunlukla önle-nebilir olması nedeniyle dikkat edilmesi gereken bir sağlık problemidir. Çalışmamızda, 6-11 yaş arası çocuklarda obezite sıklığı ve gelişiminde rol oynayan faktörleri araştırdık.Yöntem: Ankara'nın Yenimahalle ilçesinde bulunan 71 ilköğretim okulundan küme örneklem ile rastgele seçilen 32'sinde 6-11 yaş arasındaki 3963 çocuk ve ebeveynleri çalışmaya alındı. Çocukların ve ebeveynlerinin yaş, boy, kilo ve cinsiyetleri, çocukların iştah durumu, hazır yiyecekleri (atıştırma) tüketme sıklıkları, ebeveynlerin eğitim ve gelir durumları ve çocukların televizyon ve bilgisayar başında geçirdikleri süre değerlendirildi. Katılımcıların beden kit-le indeksleri hesaplanarak sosyo-demografik özellikleri ile karşılaştırıldı. Bulgular: Çocukların %11,1'i (s=438) kilolu ve %7,5'i (s=299) obez olarak saptandı. Hem anne hem de babası obez olan çocuk-larda obezite görülme sıklığı %15,7 (s=18) idi. Anne ve babaların beden kitle indeksleri arttıkça çocuklardaki obezite sıklığının da arttığı saptandı (p<0,001). Obez çocukların %64,9'unun ebeveynleri, çocuklarının kilosundan memnundu. Hem anne hem de baba obez olanlarda ise çocuklarının kilosundan memnun olma sıklığı %72,2 olarak bulundu. Her üç çocuktan ikisinin yemek öğünlerinde sorunu vardı ve çocukların %48,2'sinin düzenli sabah kahvaltısı alışkanlığı yoktu. Tüm çocukların %69,6'sının öğün aralarında abur-cubur atıştırma alışkanlığı vardı. Televizyon veya bilgisayar karşısında daha fazla vakit geçiren çocuklarda obezite görülme sıklığı anlamlı düzeyde yüksek bulundu (p<0,05).Sonuç: Çalışmamızın temel sonuçları çocukluk obezitesinde beslenme alışkanlıkları ve sedanter yaşamın önemli rol oynadığı şeklindedir.Anahtar sözcükler: Obesite, çocuk, beslenme alışkanlıkları. SummaryObjective: Childhood obesity is a health problem that should be taken into account for the fact that it progresses as adult obesity; serious increases occur in morbidity and mortality due to complications; and most importantly, it can be generally prevented. In our study, we researched obesity frequency in child-ren at 6-11 years of age, and the factors that play a role in its development. Methods: 3963 children at 6-11 years of age from 32 of 71 elementary schools located in Yenimahalle district of Ankara along with their parents were selected to participate in the study. Age, height, weight, and gender of children and their parents; appetites of the children; their frequency of consuming fast food; their parents' level of education and income; and the time spent by the children on TV and computer were evaluated. BMI (body mass index) values of the participants were calculated and compared with their socio-demographic characteristics.Results: It was found that 11.1% (n=438) of the children were overweight, and 7.5% (n=299) of them were obese. Frequency of obesity was 15...

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“…1). However, the intergenerational transmission of obesity and related chronic diseases is not a simple mechanism, and other factors, such as genetic or ethnic predisposition, gene-environment interaction, dietary and physical activity habits, socioeconomic status and environmental factors, may be determinants of health status at each period of life [50].…”

Section: Maternal Obesity and Diabetesmentioning

confidence: 99%

Early life obesity and chronic kidney disease in later life

Yim

Yoo

2014

Pediatr Nephrol

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The prevalence of chronic kidney disease (CKD) has increased considerably with a parallel rise in the prevalence of obesity. It is now recognized that early life nutrition has life-long effects on the susceptibility of an individual to develop obesity, diabetes, cardiovascular disease and CKD. The kidney can be programmed by a number of intrauterine and neonatal insults. Low birth weight (LBW) is one of the most identifiable markers of a suboptimal prenatal environment, and the important intrarenal factors sensitive to programming events include decreased nephron number and altered control of the renin-angiotensin system (RAS). LBW complicated by accelerated catch-up growth is associated with an increased risk of obesity, hypertension and CKD in later life. High birth weight and exposure to maternal diabetes or obesity can enhance the risk for developing CKD in later life. Rapid postnatal growth per se may also contribute to the subsequent development of obesity and CKD regardless of birth weight and prenatal nutrition. Although the mechanisms of renal risks due to early life nutritional programming remain largely unknown, experimental and clinical studies suggest the burdening role of early life obesity in longstanding cardiovascular and renal diseases.

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A Review on the Genetic, Environmental, and Lifestyle Aspects of the Early-Life Origins of Cardiovascular Disease

Cited by 137 publications

References 272 publications

Underweight and Obesity in Low Birth Weight Children in Early Infancy in Japan

Underweight and Obesity in Low Birth Weight Children in Early Infancy in Japan

Obesity frequency in school children and related risk factors

Early life obesity and chronic kidney disease in later life

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