2016
DOI: 10.5415/apallergy.2016.6.2.120
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A review on the role of moisturizers for atopic dermatitis

Abstract: Effective management of atopic dermatitis (AD) involves the treatment of a defective skin barrier. Patients with AD are therefore advised to use moisturizers regularly. To date, there are few comparative studies involving moisturizers in patients with AD, and no classification system exists to objectively determine which types of moisturizers are best suited to specific AD phenotypes. With this in mind, a group of experts from allergy and immunology, adult and pediatric dermatology, and pediatrics centers with… Show more

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Cited by 56 publications
(56 citation statements)
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“…Interestingly, similar increases in S subclass and increases in the fraction of C34 chain length ceramides were observed in AD (8,17). An essential application of this formulation could be in a particular group of AD patients, where barrier-restoring lipophilic formulations are commonly used (52). Moreover, the treatment presented here modulated the alterations in lipid composition observed in AD toward a healthy lipid homeostasis.…”
Section: + + Ds P H Ssupporting
confidence: 59%
“…Interestingly, similar increases in S subclass and increases in the fraction of C34 chain length ceramides were observed in AD (8,17). An essential application of this formulation could be in a particular group of AD patients, where barrier-restoring lipophilic formulations are commonly used (52). Moreover, the treatment presented here modulated the alterations in lipid composition observed in AD toward a healthy lipid homeostasis.…”
Section: + + Ds P H Ssupporting
confidence: 59%
“…Dermatologists should see counseling on skin care as an opportunity to nurture the patient‐doctor relationship, counsel on sun protection, and provide tailored advice for skin care geared toward patient needs. It is also an opportunity to advise on skin care for common dermatologic conditions, such as acne, rosacea, psoriasis, and atopic dermatitis which have been shown to significantly benefit from over‐the‐counter skin care regimens …”
Section: Discussionmentioning
confidence: 99%
“…Moisturizers were shown to improve barrier function, with the additional beneficial effect of reducing inflammatory products. 52,[169][170][171] Use of moisturizers in premature newborns decreases TEWL, dermatitis severity, and bacterial colonization. [172][173][174] An initial small study suggested that petrolatum can be used for primary AD prevention.…”
Section: Primary Prevention Supporting and Supplementing Barrier Funcmentioning
confidence: 99%