A Review on the Use of the HPV Vaccine in the Prevention of Cervical Cancer

Abstract

The main risk factor for invasive cervical carcinoma is persistent infection by the high-risk human papillomavirus (HPV). HPV is the most prevalent sexually transmitted infection (STI) and has been linked to 15 different cancers. Cervical cancer is one of the most frequent cancers among women, particularly in resource-limited countries. Cervical cancer is an HPV disease with the highest worldwide burden in resource-limited nations. With improved medical care and nationwide screening programmes, the mortality rate from cervical cancer has decreased in the past 40 years. Many developing nations have been shown to have inadequate knowledge and health-seeking practices, making proper awareness and immunisation programmes necessary. The best strategy to reduce the incidence of cervical cancer is through the administration of HPV vaccines along with routine cervical screening. The HPV vaccine is crucial for public health. Vaccinations against all HPV subtypes, namely, bivalent, quadrivalent, and nonavalent, are available. Financial issues are the main barrier to HPV vaccination. The framework for behavioural and social drivers of vaccination, which includes practical concerns, motivation, social processes, thoughts, and feelings, is widely used to uncover important aspects linked with HPV vaccination. The burden of cervical cancer due to HPV and the advantages of HPV vaccination are summarised in this review article.

Awareness of HPV vaccine and its socio-demographic determinants among the parents of eligible daughters in Bangladesh: A nationwide study

“…The HPV is a pervasive viral infection that poses a significant global public health concern due to its association with CC, among other malignancies [ 25 ].Vaccination against HPV has proven to be a powerful preventive measure against these potentially life-threatening diseases [ 26 ]. However, adequate awareness and understanding of the HPV vaccine, particularly among parents with daughters, are paramount for the successful implementation and uptake of the vaccine.…”

Improving Women's Health in the 21st Century: Current Challenges, Medical Advancements and Future Prospects

“…Groundbreaking studies demonstrate its safety and effectiveness against a gamut of potentially life-altering HPV-related health conditions. From cervical cancer to many other perilous maladies, the vaccine is an epoch-making beacon of hope and renewal for the female populace embroiled in this battle [31,32].…”

“…Embracing this paradigm shift, the American Cancer Society now recommends HPV testing as the primary screening test for females aged 25 and above. Furthermore, research suggests that this screening system can almost completely eradicate cervical cancer in low-income countries, making it the key for women to realize a life without such a fearful disease [31].…”

Perceptions of HPV-Linked Oropharyngeal Cancer Risk Messages Among a Sample of Young Adult Men in the US: A Pilot Study

“…HPV messages framed in the context of cancer prevention could be an effective way to educate young adult men and increase their perceived risk for HPV. Similar strategies have been effective for motivating young adult women and parents of adolescent girls to get the vaccine ( Pathak et al, 2022 ). For example, a cervical cancer communication campaign for college women reported that messages designed to increase awareness of susceptibility of HPV and acceptability of the HPV vaccine influenced participants’ self-reported vaccination likelihood ( Sundstrom et al, 2018 ).…”