In this paper, we study the forward and the backward in time problems for a class of nonlinear diffusion equations with respect to the pseudo‐differential operator. Herein, we investigate the stability of the solution of the forward problem in relationship with parameters of the pseudo‐differential operator and initial data. Besides, as known, the backward in time problem is instability. Hence, we give a method to regularize the solution of the backward problem in the case of the parameters are perturbed.