A Role for Oxytocin-Like Receptor in Social Habituation in a Teleost

Weitekamp, Chelsea A.; Solomon‐Lane, Tessa K.; Valle, Pamela Del; Triki, Zegni; Nugent, Bridget M.; Hofmann, Hans A.

doi:10.1159/000464098

Cited by 14 publications

(7 citation statements)

References 58 publications

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“…Although several studies report expression levels for ITR in teleost brain (e.g., DeAngelis et al, 2018;Tripp et al, 2018;Weitekamp et al, 2017), there are no brain atlases of ITR expression sites in teleosts comparable in scope to the current report other than an earlier one for an African cichlid, Astatotilapia burtoni (Huffman et al, 2012). Like several other cichlid species (Bertucci et al, 2012;Myrberg et al, 1965), A.…”

Section: Comparisons With Other Teleostsmentioning

confidence: 44%

Oxytocin‐like receptor expression in evolutionarily conserved nodes of a vocal network associated with male courtship in a teleost fish

Schuppe

Zhang

Perelmuter

et al. 2021

J of Comparative Neurology

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Neuropeptides, including oxytocin-like peptides, are a conserved group of hormones that regulate a wide range of social behaviors, including vocal communication. In the current study, we evaluate whether putative brain sites for the actions of isotocin (IT), the oxytocin (OT) homolog of teleost fishes are associated with vocal courtship and circuitry in the plainfin midshipman fish (Porichthys notatus). During the breeding season, nesting males produce advertisement calls known as "hums" to acoustically court females at night and attract them to nests. We first identify IT receptor (ITR) mRNA in evolutionarily conserved regions of the forebrain preoptic area (POA), anterior hypothalamus (AH), and midbrain periaqueductal gray (PAG), and in two topographically separate populations within the hindbrain vocal pattern generator-durationcoding vocal prepacemaker (VPP) and amplitude-coding vocal motor nuclei (VMN) that also innervate vocal muscles. We also verify that ITR expression overlaps known distribution sites of OT-like immunoreactive fibers. Next, using phosphorylated ribosomal subunit 6 (pS6) as a marker for activated neurons, we demonstrate that ITR-containing neurons in the anterior parvocellular POA, AH, PAG, VPP, and VMN are activated in humming males. Posterior parvocellular and magno/gigantocellular divisions of the POA remain constitutively active in nonhumming males that are also in a reproductive state. Together with prior studies of midshipman fish and other vertebrates, our Abbreviations: ac, anterior commissure; AH, anterior hypothalamus; AT, anterior tuberal nucleus of hypothalamus; Cc, cerebellar crest; Cg, granule cell layer of the corpus of the cerebellum; Cm, molecular layer of the cerebellum; CP, central posterior nucleus; Cpost, posterior commissure; D, area dorsalis of telencephalon; Dc, central zone of D; Dd, dorsal zone of D; DIL, diffuse nucleus of the inferior lobe; DiV, diencephalic ventricle; Dl, lateral zone of D; Dm, medial zone of D; Dm-p, posterior division of Dm; DOdm, dorsomedial division of descending octaval nucleus; DOri/I, rostral intermediate/intermediate division of descending octaval nucleus; DPo, dorsal posterior nucleus of the thalamus; ECL, external cellular layer of the olfactory bulb; GL, glomerular layer of olfactory bulb; Had, dorsal division of the habenula; Hav, ventral division of the habenula; Hb, habenula; Hd, dorsal zone, periventricular hypothalamus; HoCo, horizontal commissure; Hv, ventral zone,

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Section: Comparisons With Other Teleostsmentioning

confidence: 44%

Oxytocin‐like receptor expression in evolutionarily conserved nodes of a vocal network associated with male courtship in a teleost fish

Schuppe

Zhang

Perelmuter

et al. 2021

J of Comparative Neurology

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“…assay rodents [44] rodents [27] rodents [45] enzyme-linked immunosorbent assay (ELISA) [23] birds [46] radioimmunoassay (RIA) [19] liquid chromatography-mass spectrometry (LC-MS) [47] immunohistochemistry (IHC) [48] mRNA quantification [49] royalsocietypublishing.org/journal/rstb Phil. Trans.…”

Section: Oxytocin and Participation In Group Conflictmentioning

confidence: 99%

Oxytocin has ‘tend-and-defend’ functionality in group conflict across social vertebrates

Triki

Daughters

Dreu

2022

Phil. Trans. R. Soc. B

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Across vertebrate species, intergroup conflict confronts individuals with a tension between group interests best served by participation in conflict and personal interest best served by not participating. Here, we identify the neurohormone oxytocin as pivotal to the neurobiological regulation of this tension in distinctly different group-living vertebrates, including fishes, birds, rodents, non-human primates and humans. In the context of intergroup conflict, a review of emerging work on pro-sociality suggests that oxytocin and its fish and birds homologues, isotocin and mesotocin, respectively, can elicit participation in group conflict and aggression. This is because it amplifies (i) concern for the interests of genetically related or culturally similar ‘in-group’ others and (ii) willingness to defend against outside intruders and enemy conspecifics. Across a range of social vertebrates, oxytocin can induce aggressive behaviour to ‘tend-and-defend’ the in-group during intergroup contests. This article is part of the theme issue ‘Intergroup conflict across taxa’.

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“…Yet, such aggressive defence is significantly reduced following the blockade of oxytocin receptors in the avian brain [35]). And in social fish such as cichlids and sticklebacks, the presence of an intruder incites higher oxytocin neuronal activity [53] (also see [105]), and higher brain oxytocin levels associate with an aggressive defence of nest and territory [36].…”

Section: Responding To Out-group Threat (β)mentioning

confidence: 99%

Oxytocin has ‘Tend-and-Defend’ Functionality in Group Conflict Across Social Vertebrates

Triki¹,

Daughters²,

Dreu³

2021

Preprint

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Across vertebrate species, intergroup conflict confronts individuals with a tension between group interests best served by participation in conflict and personal interest best served by not participating. Here, we identify the neurohormone oxytocin as pivotal to the neurobiological regulation of this tension in distinctly different group-living vertebrates, including fish, birds, rodents, non-human primates, and humans. In the context of intergroup conflict, a review of emerging work on pro-sociality suggests that oxytocin and its fish and birds homologs, isotocin and mesotocin, respectively, can elicit participation in group conflict and aggression. This is because it amplifies (i) concern for the interests of genetically related or culturally similar ‘in- group’ others, and (ii) willingness to defend against outside intruders and enemy conspecifics. Across a range of social vertebrates, oxytocin can induce aggressive behaviour to ‘tend-and- defend’ the in-group during intergroup contests.

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A Role for Oxytocin-Like Receptor in Social Habituation in a Teleost

Cited by 14 publications

References 58 publications

Oxytocin‐like receptor expression in evolutionarily conserved nodes of a vocal network associated with male courtship in a teleost fish

Oxytocin‐like receptor expression in evolutionarily conserved nodes of a vocal network associated with male courtship in a teleost fish

Oxytocin has ‘tend-and-defend’ functionality in group conflict across social vertebrates

Oxytocin has ‘Tend-and-Defend’ Functionality in Group Conflict Across Social Vertebrates

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