I. Introduction A primary function of air traffic flow management is to strategically shape traffic demand to match capacities (e.g., airport arrival/departure rate limits and Sector capacities), without imposing excessive delay. In the current United States National Airspace System (NAS), the disruptions modulating capacities and hence traffic management are predominantly weather events, including convection, winter weather, and high winds. However, during the next 15 years and beyond, it is likely that the air traffic system will be increasingly subject to man-made disruptions that impact traffic management, including 1) a growing frequency of cyber-and physical-world security incidents, 2) commercial space operations, and 3) integration of high-altitude unmanned aircraft. Disruptions of these types have already begun to impact traffic control and management: for instance, the insider attack on the Chicago Air Route Traffic Control Center (ZAU) communication equipment during October 2014, and several recent commercial space launches and UAS-integration test scenarios. To date, such non-weather disruptions have had relatively contained and limited impact on air traffic system operations, but they will undoubtedly incur greater impact and cost in the near future as the airspace system becomes increasingly heterogeneous and cyber-enabled. In consequence, paradigms for traffic management that account for non-weather disruptions will be needed in the near future. The management of air traffic flows in the face of severe weather alone is a hard problem. However, because of the predominance of weather impact, traffic managers are experienced in characterizing the impact of weather on capacities, and in shaping flows to match capacity requirements. Also, the managers have available a number of tools which assist in decision-making at several time/spatial scales, and additional decision-support capabilities are under development [1,2]. Addressing non-weather disruptions in air traffic management entails several new challenges: 1) These disruptions may cause drastic recurring long-duration and/or recurring reduction in airspace capacity. For instance, space operations can require complete closure of multiple Sectors over the countdown/launch duration, and will have regular impact when commercial space operations become common. Likewise, security incidents may cause closure of major airports or even Center offices. Because of their severity, the disturbances can have NAS-wide impact on traffic. 2) Predicting capacity reduction profiles due to non-weather disruptions is challenging. On one hand, these disruptions may be pre-planned and have highly structured impact which allow for nearly deterministic models. On the other hand, however, operators have limited experience with the potential impacts, and formal models for capacity-reduction impacts may be unavailable. Also, the events themselves are often rare, and may involve uncertainties that do not easily admit statistical models (e.g., the possible delay in a launch coun...