This research purposes to study the influence of 7E LC-STEM on students' creative thinking skills in the temperature and heat topic using quasi-experiment research with Pre-and Posttest Design. The subject is students of Senior High School Batu Indonesia. They are distributed in the experiment (7E LC-STEM) and the comparison (7E LC) classes The research instrument is students' Creative Thinking Skills Test with reliability of Cronbach's alpha of 0.803. The data is analyzed with t-test, N-gain, and effect size. The result shows that the STEM approach can increase creative thinking skills as indicated by the significantly higher average skill score obtained by the experiment class. The implementation effect of 7E LC-STEM learning has a very large category than 7E LC class in increasing creative thinking skills of students. The students of experiment class give higher positive responses than the comparison class for the learning process.