Let (M, g) be a complete Riemannian manifold with nonpositive scalar curvature, let Ω ⊂ M be a suitable domain, and let λ(Ω) be the first Dirichlet eigenvalue of the Laplace-Beltrami operator on Ω. We prove several bounds for the rate of decrease of λ(Ω) as Ω increases, and a result comparing the rate of decrease of λ before and after a conformal diffeomorphism. Along the way, we prove a reverse-Hölder inequality for the first eigenfunction, which generalizes results of Chiti to the manifold setting and maybe be of independent interest.