A selected population study reveals the biochemical mechanism of intramuscular fat deposition in chicken meat

Cui, Huanxian; Liu, Lu; Liu, Xiaojing; Wang, Yongli; Luo, Na; Tan, Xiaodong; Zhu, Yuting; Liu, Ranran; Zhao, Guiping; Wen, Jie

doi:10.1186/s40104-022-00705-3

Cited by 15 publications

(9 citation statements)

References 40 publications

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“…Many metabolites involved in lipid metabolism were identified in groups G and H which may be involved in the regulation of intramuscular fat deposition. The contents of intramuscular fats are important indexes to evaluate meat quality, since they were confirmed to affect the flavor and tenderness qualities of chicken meat [ 54 ]. In this study, oil red O staining was employed to observe the distribution of lipid droplets in muscle cells.…”

Section: Resultsmentioning

confidence: 99%

The Implications in Meat Quality and Nutrition by Comparing the Metabolites of Pectoral Muscle between Adult Indigenous Chickens and Commercial Laying Hens

et al. 2023

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Aged chickens are often a secondary dietary choice, owing to the poor organoleptic qualities of their meat. With regard to the meat quality of chickens, the metabolic profiles of pectoral muscle in Guangyuan grey chickens (group G) and Hy-Line grey hens (group H) aged 55 weeks were compared via ultra-high-performance liquid chromatography–tandem mass spectrometry (UHPLC-MS/MS). A total of 74 metabolites were identified with differential changes in the ion model. Lipids and lipid-like molecules comprised the largest proportion among the different metabolites. The content of myristic acid and palmitic acid were found to be higher in the pectoral muscle of group G, while group H showed significantly higher levels of glycerophospholipid molecules, such as LPC(18:2/0:0), Pi(38:5), Pc(16:0/16:0), and Pe(16:1e/14-hdohe). KEGG pathway analysis indicated that the abundant metabolites in group G were mainly involved in energy metabolism and fatty acid biosynthesis and metabolism, whereas those of group H were mainly attributed to the metabolism of unsaturated fatty acids and amino acids. Overall, the differences in lipid and amino acid metabolism in pectoral muscle appear to be responsible for the difference in meat quality between indigenous chickens and commercial laying hens.

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Section: Resultsmentioning

confidence: 99%

The Implications in Meat Quality and Nutrition by Comparing the Metabolites of Pectoral Muscle between Adult Indigenous Chickens and Commercial Laying Hens

et al. 2023

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“…At the same time, physicians may still retrieve important and useful information for an individual therapeutic application. Furthermore, this technique could as well be valuable to the food industry and farmers who want to determine the quality of meat by analyzing the IMF, as evidenced by studies exploring the "official beef marbling standard" or assessing chicken meat quality using histological methods [64] , [65] . In all these situations it is desirable to have a cost-effective and objective quantification as provided by IMFSegNet.…”

Section: Discussionmentioning

confidence: 99%

IMFSegNet: Cost-effective and objective quantification of intramuscular fat in histological sections by deep learning

Praetorius

Walluks

Svensson

et al. 2023

Computational and Structural Biotechnology Journal

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“…IMF, the lipid mixture in the muscle tissue [ 6 ], is a complex quantitative trait with medium-low heritability [ 31 , 32 ]. It was confirmed that TG is a representative index of IMF in chicken, and its content determines the IMF content [ 33 ]. Therefore, the TG deposition regulation is critical to elucidating the genetic mechanism of IMF deposition in chickens.…”

Section: Discussionmentioning

confidence: 99%

SLC16A7 Promotes Triglyceride Deposition by De Novo Lipogenesis in Chicken Muscle Tissue

Wang

Liu

et al. 2022

Biology

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Triglyceride (TG) content in chicken muscle tissue signifies intramuscular fat (IMF) content, which is important for improving meat quality. However, the genetic basis of TG deposition in chicken is still unclear. Using 520 chickens from an artificially selected line with significantly increased IMF content and a control line, a genome-wide association study (GWAS) with TG content reports a region of 802 Kb located in chromosome 1. The XP-EHH and gene expression analysis together reveal that the solute carrier family 16 member A7 (SLC16A7) gene is the key candidate gene associated with TG content in chicken muscle tissue. Furthermore, the weighted gene co-expression network analysis (WGCNA) confirmed the regulatory effects of SLC16A7 on promoting TG deposition by de novo lipogenesis (DNL). Functional verification of SLC16A7 in vitro also supports this view, and reveals that this effect mainly occurs in myocytes. Our data highlight a potential IMF deposition pathway by DNL, induced by SLC16A7 in chicken myocytes. These findings will improve the understanding of IMF regulation in chicken and guide the formulation of breeding strategies for high-quality chicken.

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A selected population study reveals the biochemical mechanism of intramuscular fat deposition in chicken meat

Cited by 15 publications

References 40 publications

The Implications in Meat Quality and Nutrition by Comparing the Metabolites of Pectoral Muscle between Adult Indigenous Chickens and Commercial Laying Hens

The Implications in Meat Quality and Nutrition by Comparing the Metabolites of Pectoral Muscle between Adult Indigenous Chickens and Commercial Laying Hens

IMFSegNet: Cost-effective and objective quantification of intramuscular fat in histological sections by deep learning

SLC16A7 Promotes Triglyceride Deposition by De Novo Lipogenesis in Chicken Muscle Tissue

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