A selective fluorescent sensor for Hg2+ based on covalently immobilized naphthalimide derivative

Wu, Xia; Ma, Qiujuan; Wei, Xiaojie; Hou, Yimin; Zhu, Xin

doi:10.1016/j.snb.2013.04.024

Cited by 56 publications

(25 citation statements)

References 54 publications

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“…Although many efforts have been made to prepare 1,8-naphthalimide derivatives with different substitutions at position 4 [1,10,11,[27][28][29][30], this manuscript reports the first attempt to simultaneously design and synthesize mono-and di-substituted 1,8-naphthalimide derivatives at position 4. N-n-Butyl-4-bromo-1,8-naphthalimide was prepared by the convenient substitution of 4-bromo-1,8-naphthlic anhydride with n-butylamine.…”

Section: Synthesis and Characterizationmentioning

confidence: 99%

“…The naphthalene moiety is an ideal fluorophore, and its derivatives have been widely applied as fluorescent dyes, metal sensors, optical sensors and organic light-emitting materials because of their high absorption coefficients, high fluorescence and quantum yields, large Stokes shifts, good photostability and easy modification [6][7][8][9]. In recent years, naphthalimide-based probes have been developed to detect H + , Hg 2+ , Zn 2+ , Cu 2+ , Ag + , Cd 2+ , Pd 2+ , Cr 3+ , Al 3+ , Fe 3+ , and F -via chromogenic and fluorogenic analyses [10][11][12][13][14][15][16]. Therefore, the naphthalimide derivatives are potential carriers that could be used in the preparation of new optical chemosensors.…”

Section: Introductionmentioning

confidence: 99%

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Synthesis and Fluorescent Properties of Novel Mono- and Di-Substituted 1,8-Naphthalimide Derivatives at the <em>C</em>-4 Position

Fu¹,

Pang²,

Wang³

et al. 2017

Preprint

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A series of novel N-n-butyl-1,8-naphthalimide derivatives were synthesized via a three-step reaction involving nucleophilic substitution and acylation. All of the compounds were characterized by IR, 1 H NMR, 13 C NMR, MS, and elemental analysis, and the crystal structure of N-n-butyl-4-[N',N'-bis(2`,4`-dichlorobenzoyl)ethylamino]-1,8-naphthalimide was determined. The π-π stacking interactions and hydrogen bonds between the two molecular core planes (naphthalimide ring) and the van der Waals forces between the flexible n-butyl groups resulted in a 3D long-chain structure. The UV-vis and fluorescence properties of the title compounds were investigated. The results indicated that the monosubstituted 1,8-naphthalimide derivatives bearing an electron-donating group on the benzene ring or a structure with a larger conjugative effect exhibited enhanced fluorescence properties.

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Section: Synthesis and Characterizationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Synthesis and Fluorescent Properties of Novel Mono- and Di-Substituted 1,8-Naphthalimide Derivatives at the <em>C</em>-4 Position

Fu¹,

Pang²,

Wang³

et al. 2017

Preprint

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show abstract

“…Ag + and Cu 2+ ) completely quenched the fluorescence emission. For the development of immobilized Hg 2+ sensors, the naphthalimide derivative with a terminal double bond was prepared and photo-copolymerized with 2-hydroxyethyl methacrylate on a glass surface (60). The resulting sensor underwent FE induced by PET inhibition process in the presence of Hg 2+ .…”

Section: Table 2 Comparison Of Fluorogenic Sensing Characteristics Fmentioning

confidence: 99%

Synthesis of Fluorogenic Chemosensors for Hg²⁺Detection Using Naphthalimide Derivatives

Lee

Jang

Den

et al. 2014

ACS Symposium Series

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Mercury ions are considered as severe environmental pollutants as they are widely spread in the atmosphere and surface water from either natural or anthropogenic activities. Current practices in detecting the ions involve sophisticated and costly analytical techniques including atomic absorption spectrometry, atomic emission spectrometry and inductively coupled plasma/mass spectrometry. Fluorogenic chemosensors, on the other hand, offer the unique advantages of high selectivity, high sensitivity, long lifetime and relatively low costs. This study focuses on reviewing current development of fluorogenic chemosensors in mercury ions detection, based on the use of naphthalimide or non-naphthalimide derivatives. The design principles as well as photophysical properties for the fluorogenic chemosensors are discussed. This study concludes with future perspectives of chemosensor design, including employment of C=N isomerization mechanism for fluorescence improvement and utilization of crown ether for improved recognition of mercury ions.

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“…7,8 Therefore, it is essential to develop a sensitive and selective method to monitor mercury(II) ion (Hg 2+ ) to ensure the public health. 17 Accordingly, there is a great demand for establishing a simple, cost-effective and rapid method for field monitoring of mercury. 16 Although these methods are sensitive and selective, their inherent weaknesses limit their practical application to some extent, involving expensive and highly specialized apparatus, and complex and inconvenient operation.…”

Section: Introductionmentioning

confidence: 99%

Flow injection chemiluminescence immunoassay based on resin beads, enzymatic amplification and a novel monoclonal antibody for determination of Hg²⁺

Chen

Dong

et al. 2015

Analyst

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In the present work, a simple and sensitive flow injection chemiluminescent competitive immunoassay was developed for the determination of mercury(II) ion (Hg(2+)) based on carboxylic resin beads, a novel specific monoclonal antibody (McAb) and HRP enzyme-amplification. Resin beads with carboxyl groups were creatively employed as supports for immobilizing more coating antigen through acylamide bonds. With a competitive-type assay mode, the Hg(2+) in solution competed with the immobilized coating antigen for the limited McAb. Then, the second antibody labeled with HRP was introduced, and an effectively increased CL was obtained, which was ascribed to the catalytic activity of HRP for the luminol-PIP-H2O2 reaction. With increasing concentration of Hg(2+), the CL of this system decreases because less HRP is present in the CL reaction. At optimal conditions, the CL signal displayed a good linear relation toward Hg(2+) in the range of 0.05-200 ng mL(-1) with a detection limit (3σ) of 0.015 ng mL(-1). The immunosensor possessed high specificity, acceptable accuracy and reproducibility, and was examined in real samples with favorable results. This immunoassay will have intriguing application prospects for the determination of other heavy metal ions and environmental contaminants.

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A selective fluorescent sensor for Hg2+ based on covalently immobilized naphthalimide derivative

Cited by 56 publications

References 54 publications

Synthesis and Fluorescent Properties of Novel Mono- and Di-Substituted 1,8-Naphthalimide Derivatives at the <em>C</em>-4 Position

Synthesis and Fluorescent Properties of Novel Mono- and Di-Substituted 1,8-Naphthalimide Derivatives at the <em>C</em>-4 Position

Synthesis of Fluorogenic Chemosensors for Hg²⁺Detection Using Naphthalimide Derivatives

Flow injection chemiluminescence immunoassay based on resin beads, enzymatic amplification and a novel monoclonal antibody for determination of Hg²⁺

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A selective fluorescent sensor for Hg2+ based on covalently immobilized naphthalimide derivative

Cited by 56 publications

References 54 publications

Synthesis and Fluorescent Properties of Novel Mono- and Di-Substituted 1,8-Naphthalimide Derivatives at the <em>C</em>-4 Position

Synthesis and Fluorescent Properties of Novel Mono- and Di-Substituted 1,8-Naphthalimide Derivatives at the <em>C</em>-4 Position

Synthesis of Fluorogenic Chemosensors for Hg2+Detection Using Naphthalimide Derivatives

Flow injection chemiluminescence immunoassay based on resin beads, enzymatic amplification and a novel monoclonal antibody for determination of Hg2+

Contact Info

Product

Resources

About

Synthesis of Fluorogenic Chemosensors for Hg²⁺Detection Using Naphthalimide Derivatives

Flow injection chemiluminescence immunoassay based on resin beads, enzymatic amplification and a novel monoclonal antibody for determination of Hg²⁺