A selective hydrolytic and restructuring approach through a Schiff base design on a coumarin platform for “turn-on” fluorogenic sensing of Zn²⁺

Abstract

The designed molecular probe, CMD, undergoes Zn2+ triggered restructuring and shows a fluorescence change in only 30 seconds. The LOD was found to be of sub-nanomolar level.

Luminescence and Electrochemical Activity of New Unsymmetrical 3-Imino-1,8-naphthalimide Derivatives

“…Nevertheless, the use of imines in biological research is associated with the possibility of hydrolysis of these compounds [24]. However, the imines described in the literature, which underwent hydrolysis and had a significant impact on the properties, most often contained a unit with an imine bond in their structures, capable of complexing ions [25][26][27][28][29][30][31][32]. It should be noted that earlier studies have shown that, despite partial hydrolysis of the compounds, biological activity was associated with the presence of non-hydrolyzed imine [26].…”

ESIPT-Active 8-Hydroxyquinoline-Based Fluorescence Sensor for Zn(II) Detection and Aggregation-Induced Emission of the Zn(II) Complex

“…The corresponding plot of fluorescence intensity versus the concentration of Zn 2+ was constructed and a good linear relationship was observed over the range of 2∼15 μM (Figure S4). Based on the rule of 3σ/slope, − the detection limit of HL to Zn 2+ in THF/H 2 O (3:7, v/v) was estimated to be 1.07 × 10 –7 M. The UV–vis absorption spectra of HL at variable concentrations in THF/H 2 O (3:7, v/v) were also measured and are presented in Figure S5a. There are two peaks centered at 265 and 316 nm corresponding to π–π* and n –π* transitions, respectively.…”

Synthesis, Characterization and Biological Evaluation of New Schiff Base Ligand derived from 3-hydroxy-benzaldehyde and p-toluidine and its Divalent Metal Ions

“…Peaks were detailed on BRUKER 300 MHz instrument by using CDCl3 as solvent. One singlet peak was observed for CH3 group, one broad peak at δ 5.025 ppm shows residual NH2, aromatic benzene ring protons were shown in the form of multiplet at δ 7.562-6.743 ppm, one more deshielded singlet was recorded at δ 8.404 ppm for (-CH=N-) proton, one singlet was observed at δ 9.890 ppm for OH group [33,34].…”