The continuous exploration of cleanâenergy technology is critical for the sustainable development of society. The recent work on the electric energy harvesting from water evaporation has made a significant contribution to the utilization of clean energy for selfâpowering systems. Here, a novel metalâorganicâframeworkâbased hybrid nanomaterial is delicately designed and synthesized by the growth of UIOâ66 nanoparticles on 2D AlOOH nanoflakes. Due to the combined merits from the 2D morphology, which is inherited from the AlOOH nanoflakes, and the high surface potential, which originates from the UIOâ66 nanoparticles, the device made of the AlOOH/UIOâ66 hybrid nanomaterials can harvest electric energy from natural water evaporation. An openâcircuit voltage of 1.63 ± 0.10 V can be achieved on the prototype devices made of the hybrid nanomaterial. As a proofâofâconcept application, a small electric appliance, e.g., a digital calculator, is powered up by a 3 Ă 3 device array connected in a combined seriesâparallel configuration.