A self-reported long-term follow-up of patients operated with either shortening techniques or a TachoSil grafting procedure

Horstmann, Marcus; Kwol, Matthias; Amend, Bastian; Hennenlotter, Joerg; Stenzl, Arnulf

doi:10.1038/aja.2010.157

Cited by 26 publications

(22 citation statements)

References 33 publications

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“…Curvature recurrence rates were conveyed between 4-27% in the same studies. [2,9,10,[13][14][15][16] The recurrent cases who underwent SP were predominated by bi-planar curvatures (50%) and recurring side was lateral in general in our series. Therefore instead of suture/ tissue problems, cavernosal anatomy which is weaker at the lateral sides may be blamed for the recurrences.…”

Section: Discussionmentioning

confidence: 80%

Peyronie`s disease surgery: Surgical outcomes of 268 cases

Kadıoğlu

Salabaş

Özmez

et al. 2018

Turkish Journal of Urology

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Objective: To assess the outcomes of the surgical techniques used in Peyronie's disease (PD) surgery. Material and methods:Two hundred and sixty-eight patients received surgical treatment for PD. Fifty four and 144 patients underwent simple corporoplasties (shortening procedure, SP, group 1) or plaque incision and grafting surgery (lengthening surgery, LP, group 2), respectively, whereas 70 patients with erectile dysfunction underwent penile prosthesis implantation.Results: Penile plication and Nesbit surgeries were performed in 5 (9%) and 42 (78%) patients out of total 54 patients. In the remaining 7 (13%) patients, Nesbit and plication suture combination was required for complete penile straightening. Mean curvature degree was 52.2±12.3 degrees. Follow up time was 36.1±29.4 months. No significant difference was demonstrated between the two groups in the baseline features and co-morbidities except age. In 144 patients who underwent plaque incision and grafting, mean age and PD onset duration were 54.1±9.2 years and 28.2±17.3 months respectively. Mean curvature degree was 58.4±18.9 degrees. Post-operative follow up time of the second group was 51.1±39.6 months. Additional plication suture was used in 48 patients (33%) patients. Degree of curvature improvement was 37.9±19.1 and 52.1±23.5 in SP and LP respectively (p=0.01). The initial anatomic success rates were 90.4% and 87.5% at their early post-operative follow-ups for group 1 and 2 respectively. These rates dropped to 82.7% and 83.6% at the long term follow-up (36 and 51 months) respectively (p=0.9). Although the average follow-up time of LP group was longer than SP group (52.1 mo vs. 37.0 mo), recurrence rates of these two groups were comparable. The combined functional and anatomical success of patients were demonstrated to be 79% and 75% in shortening and grafting surgery. Shortening surgery was not statistically superior to grafting surgery for patients in terms of having erection with or without the aid of PDE-5 inhibitors (94.4% vs. 88.2%, p=0.28). Shortening surgery makes a difference in the long term follow-up for patients who had erections without the aid of p=0.02). Conclusion:Both SP and LP are successful in terms of penile straightening in the short and long-term follow-up. Curvature degree improvement is greater in LP. Patients who undergo LP surgery may suffer from ED in the long-term follow-ups. Greater percentage of patients who underwent LP require PDE-5 inhibitors usage for sexual intercourse. Despite stated shortcomings, combined success (anatomic and functional) is achieved in three out of four patients for both groups. Penile prosthesis implantation should be preferred for patients with ED and penile deformity.

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Section: Discussionmentioning

confidence: 80%

Peyronie`s disease surgery: Surgical outcomes of 268 cases

Kadıoğlu

Salabaş

Özmez

et al. 2018

Turkish Journal of Urology

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“…The shortening rates observed by Horstmann et al . (93%) (Horstmann et al ., ), together with the fact that the data are very recent, suggest the results should be interpreted with caution. In the case of SIS and pericardium, both of which widely used, the data seem to be quite similar (success rates of 53.8–91% and ED 11–63% compared with success rates of 55.6–100% and ED 0–55.6% for SIS).…”

Section: Discussionmentioning

confidence: 95%

Grafts for Peyronie's disease: a comprehensive review

et al. 2017

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The difficulty implicit in combining all the characteristics that an ideal patch to treat Peyronie's disease with a lengthening procedure should have, together with the challenges of comparing results from different series, means that the ideal patch has yet to be determined. Our objective with this review was to determine whether any given patch type is preferable to the others based on the evaluation of the results of published studies. A systematic search of the literature was conducted from PubMed until December 2016. Articles reporting basic research, animal research, reviews or meta-analyses and studies in children were eliminated. Series with patients undergoing some kind of other surgical intervention were only included if results were reported separately. Case reports and series of five patients were excluded. Five variables were selected to evaluate the results: number of patients, follow-up period, straightening rate, shortening rate and post-operative ED rate. For this purpose, 69 papers were included for review, and the outcomes of the use of autologous dermis, tunica vaginalis, dura mater, fascia, saphenous vein, tunica albuginea, buccal mucosa, porcine intestinal submucosa, pericardium, TachoSil and synthetic materials were presented and analysed separately. The different series published are extremely variable and heterogeneous in terms of the number of patients included, patient selection, follow-up periods, and in the measurement and interpretation of the outcomes analysed. Given these facts, it is not possible to draw any definitive conclusion, homogeneous, prospective studies using validated tools are required to determine which the ideal graft is.

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“…The Nesbit procedure was the original tunical shortening technique and was initially used for the correction of congenital penile curvature caused by corporal disproportion. Modifications of tunical shortening techniques include the Yachia , Giammusso , Lemberger and Essed‐Schröeder techniques, the 16‐ or 24‐dot procedure , the penoscrotal plication procedure and tunica albuginea plication (Table ).…”

Section: Outcomes Of Pd Surgical Correctionmentioning

confidence: 99%

Outcomes of surgical treatment of Peyronie's disease

Carson

Levine

2014

BJU International

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The aims of the present review were to assess the literature on published outcomes and complications associated with surgical treatments for Peyronie's disease (PD) and to assist clinicians in the effective management of PD by increasing understanding and awareness of the outcomes associated with current surgical treatment options. A PubMed literature search was conducted to identify relevant, peer‐reviewed clinical and review articles published between January 1980 and October 2013 related to outcomes of surgical correction of PD. Search terms for this non‐systematic review included ‘Peyronie's disease’, ‘outcomes’, ‘complications’, ‘erectile dysfunction or ED’, ‘patient expectation’, and ‘patient satisfaction’; search terms were searched separately and in combination. Case studies and editorials were excluded, primary manuscripts and reviews were included, and bibliographies of articles of interest were reviewed and key references were obtained. Assessment of the study design, methodology, clinical relevance and impact on the surgical outcomes of PD was performed on the sixty‐one articles that were selected and analysed. Currently, there are several investigational minimally invasive and non‐surgical treatment options for PD; however, surgical treatment remains the standard of care for patients with stable disease and disabling deformity or drug‐resistant erectile dysfunction. Each of the different surgical procedures that are used for treatment of PD, including tunical shortening, tunical lengthening (plaque incisions or partial excision and grafting), and use of inflatable penile prostheses, carries its own advantages and disadvantages in terms of potential complications and postoperative satisfaction. Because of the variety of ways that PD may present in affected patients, no single, standard, surgical treatment for this disorder has prevailed and multiple variations of each type of procedure may exist. Surgical outcomes of the most commonly used procedures are not substantially different; therefore, the appropriateness of each treatment option may often depend on disease and patient characteristics (e.g. deformity and erectile function). Surgical algorithms have been published to guide surgeons and patients through the selection of surgical procedures in the absence of conclusive, long‐term outcome data. Accumulating data on outcomes associated with established procedures, modifications to these procedures, and new surgical techniques and materials may serve to further guide practice and refine evidence‐based selection of the surgical approach.

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A self-reported long-term follow-up of patients operated with either shortening techniques or a TachoSil grafting procedure

Cited by 26 publications

References 33 publications

Peyronie`s disease surgery: Surgical outcomes of 268 cases

Peyronie`s disease surgery: Surgical outcomes of 268 cases

Grafts for Peyronie's disease: a comprehensive review

Outcomes of surgical treatment of Peyronie's disease

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