This study presents the development of a design method that has been extended to the design of radial-inflow turbines operating in organic Rankine cycles (ORC). Both the conventional design method and the circulation method available in the literature have been reviewed. The two main limitations of the current circulation method that make it not suitable for the ORC turbine design are the lack of real gas capability and 3D blades with high stresses. Using the circulation method, the flow field is decomposed into a potential part and a rotational part. The mean velocity field and the periodic velocity field are solved separately. To model the thermodynamic properties of the real gas, NIST REFPROP or CoolProp are used. The blade geometry is then solved iteratively by assuming that the velocity vector is parallel to the blade surface. The blade boundary condition is modified to force the blade camber to be radial-fibred, which is helpful to reduce the centrifugal bending stress on the blade. All the formulations are derived step by step, and the numerical treatments, including grid generation, numerical differentiation, computational scheme, and convergence, are discussed in detail. This method is validated by designing a R245fa ORC turbine rotor. The performance of the rotor design is predicted by CFD and FEA simulations, and it is compared to the results using other methodologies in the literature.