2022
DOI: 10.1128/aem.01740-21
|View full text |Cite
|
Sign up to set email alerts
|

A Sensitive and Rapid Wastewater Test for SARS-COV-2 and Its Use for the Early Detection of a Cluster of Cases in a Remote Community

Abstract: Throughout the COVID-19 pandemic, wastewater surveillance has been used to monitor trends in SARS-CoV-2 prevalence in the community. A major challenge in establishing wastewater surveillance programs, especially in remote areas, is the need for a well-equipped laboratory for sample analysis. Currently, no options exist for rapid, sensitive, mobile, and easy-to-use wastewater tests for SARS-CoV-2. The performance of the GeneXpert System, which offers cartridge-based, rapid molecular clinical testing for SARS-Co… Show more

Help me understand this report
View preprint versions

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

0
12
0

Year Published

2022
2022
2024
2024

Publication Types

Select...
9
1

Relationship

0
10

Authors

Journals

citations
Cited by 24 publications
(12 citation statements)
references
References 47 publications
0
12
0
Order By: Relevance
“…This is a significant problem because under-reporting may lead to a false sense of security among the public and hinder data-driven decisions by policymakers. Overall, this study indicates the need to continue regular surveillance and heed the warnings of viral genome concentrations in the wastewater as a representative indicator of community health as well as COVID-19 cases in the area [6,[30][31][32][33]. Smaller communities do not always have access to the same resources or information available in larger cities.…”
Section: Discussionmentioning
confidence: 92%
“…This is a significant problem because under-reporting may lead to a false sense of security among the public and hinder data-driven decisions by policymakers. Overall, this study indicates the need to continue regular surveillance and heed the warnings of viral genome concentrations in the wastewater as a representative indicator of community health as well as COVID-19 cases in the area [6,[30][31][32][33]. Smaller communities do not always have access to the same resources or information available in larger cities.…”
Section: Discussionmentioning
confidence: 92%
“…However, sensitivity is acceptable at concentrations over 32 copy/mL in wastewater. Without concentration, the findings should be considered qualitative [26].…”
Section: Discussionmentioning
confidence: 99%
“…Recently, a significant number of studies have been published that improve confidence in the ability of WBE to assess SARS-CoV-2 transmission in the community. The topics addressed by these studies range from assessment and normalization of SARS-CoV-2 RNA in wastewater to a better understanding of the relationship between RNA load and COVID-19 clinical cases and hospitalization. The unique feature of our study is the evaluation of the relationship between wastewater RNA load and COVID-19 in an underserved community and the importance of elevating visibility of these communities to public health authorities.…”
Section: Discussionmentioning
confidence: 99%