A sensitive and selective fluorescent sensor for Zinc(II) and its application to living cell imaging

Zinc(II) and pyrophosphate selective fluorescence probe and its application to living cell imaging

“…Disorders in Zn 2+ metabolism have been connected to several neurological diseases, including Alzheimer's disease (AD) [4,5], cerebral ischemia [6], and epilepsy [7]. Therefore, the development of techniques for Zn 2+ detection in biological processes has been an important research topic [8][9][10][11][12][13][14][15][16][17][18][19][20][21][22].…”

Applications of Nanomaterials Based on Magnetite and Mesoporous Silica on the Selective Detection of Zinc Ion in Live Cell Imaging

“…Compared with other similar detection systems that have been described in the literature, the nanoparticles that were reported here showed a higher sensibility for being able to detect the target metal in the cells that were supplemented with only 10 µM Zn 2+ . Conversely, recent studies with other nanoparticles or organic compounds described lower sensibility, showing a higher detection limit of Zn 2+ concentration, for example 20 µM [ 71 ], 25 µM [ 72 ], or even 10 mM [ 73 ].…”

A multifunctional magnetic core–shell fibrous silica sensing probe for highly sensitive detection and removal of Zn2+ from aqueous solution

“…However, there are some important factors that can limit their practical application in the environmental systems: (1) their poor solubilities in the aqueous solution; 22,[28][29][30] (2) complicated synthesis process; [30][31][32] (3) poor performance for removal of excess Zn 2+ from the environmental samples. Hence, it remains a challenge to explore new or improved methods for the selective evaluation of Zn 2+ and the easy removal of excessive Zn 2+ ion in aqueous environment.…”

“…Recently, various fluorescent chemosensors for Zn 2+ have been developed using coumarin, 19,20 quinoline, 21,22 indole, 23 1,8-naphthalimide, 24,25 bipyridine, 26 and other fluorophores, 27 which showed excellent selectivity and sensitivity towards Zn 2+ ions. However, there are some important factors that can limit their practical application in the environmental systems: (1) their poor solubilities in the aqueous solution; 22,[28][29][30] (2) complicated synthesis process; [30][31][32] (3) poor performance in the removal of excess Zn 2+ from the environmental samples. Hence, it remains a challenge to explore new or improved methods for the selective evaluation of Zn 2+ and the easy removal of excessive Zn 2+ ions in aqueous environments.…”