A sensitive electrochemical aptasensor for zearalenone detection based on target-triggered branched hybridization chain reaction and exonuclease I–assisted recycling

Liao, Zhibing; Guo, Wentao; Ning, Guobin; Wu, Yaohui; Wang, Yonghong; Ge, Ning

doi:10.1007/s00216-023-04797-2

Cited by 6 publications

(1 citation statement)

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“…Nevertheless, some authors consider that electrochemical sensors, mostly those using aptamers as bioelements, though simple, sensitive, fast, and cost-effective, still require signal amplification protocols for sensitivity increase. In a novel electrochemical assay, sensitivities of the order of pM were obtained using exonuclease I and branched hybridization chain reaction of the biorecognition element, promoting signal amplification for zearalenone differential pulse voltammetric detection [163].…”

Section: Comparative Overview and Future Perspectivementioning

confidence: 99%

Biosensors for Food Mycotoxin Determination: A Comparative and Critical Review

Pisoschi,

Iordache,

Stanca

et al. 2024

Chemosensors

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The need for performant analytical methodologies to assess mycotoxins is vital, given the negative health impact of these compounds. Biosensors are analytical devices that consist of a biological element for recognizing the analyte and a transducer, which translates the biorecognition event into a signal proportional to the analyte concentration. The biorecognition elements can be enzymes, antibodies, or DNA fragments. The modalities of detection can be optical, electrochemical, thermal, or mass-sensitive. These analytical tools represent viable alternatives to laborious, expensive traditional methods and are characterized by specificity given by the biorecognition element, sensitivity, fast response, portability, multi-modal detection, and the possibility of in situ application. The present paper focuses on a comprehensive view, enriched with a critical, comparative perspective on mycotoxin assay using biosensors. The use of different biorecognition elements and detection modes are discussed comparatively. Nanomaterials with optical and electrochemical features can be exploited in association with a variety of biorecognition elements. Analytical parameters are reviewed along with a broad range of applications.

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Section: Comparative Overview and Future Perspectivementioning

confidence: 99%