A sensitive fluorescence detection strategy for H2O2 and glucose by using aminated Fe–Ni bimetallic MOF as fluorescent nanozyme

A facile, low-cost bimetallic iron–nickel MOF nanozyme-propelled ratiometric fluorescent sensor for highly sensitive and selective uric acid detection and its smartphone application

“…1B), Fe 3 Ni-MOF-NH 2 exhibited a uniform bipyramidal shape with the length and width of around 800 nm and 100 nm, respectively. In addition, the X-ray diffraction (XRD) patterns were used to study the crystal phases of Fe 42 The synthesized MOF nanozyme demonstrated characteristic diffraction peaks which were in good accordance with those in previous work, 42 confirming their highly crystalline structure. Moreover, scanning electron microscopy (SEM) was also conducted, as displayed in Fig.…”

“…S8 †). All these parameters were just analogous to those from a previous report, 42 demonstrating the stable and reproducible catalytic activity of this material. The as-synthesized Fe 3 Ni-MOF-NH 2 nanozyme showed a lower K m value and higher V max value than those of the horseradish peroxidase (HRP) (Table S1 †), 43 indicating the superior catalytic performance of the Fe 3 Ni-MOF-NH 2 nanozyme.…”

“…Fe 3 Ni-MOF-NH 2 was synthesized according to a previous report. 42 In a typical reaction, 1 mmol of NH 2 -BDC, 0.75 mmol of FeCl 3 •6H 2 O and 0.25 mmol of Ni (NO 3 ) 2 •6H 2 O were dissolved in 20 mL of DMF. The above mixture was first homogenized under magnetic stirring at room temperature for 10 min.…”

“…Fig. 1A presents a schematic diagram of the facile synthesis of the low-cost Fe 3 Ni-MOF-NH 2 nanozyme, which was obtained through three crucial steps according to a previous report 42 (see the full details in the ESI †). As presented in the TEM image (Fig.…”

Tunable metal–organic frameworks assist in catalyzing DNAzymes with amplification platforms for biomedical applications

“…3(B), (C) and 4(A), (B)). Among them, the studied active metals are Fe–Ni, 88–90 Fe–Zr, 91 Fe–Mn, Fe–Co, 92 Cu–Zn, 92,93 Mn–Zn, 94 and Co–Mn–Zn. 95 The electron density difference map of [Fe 2 Ni 4 ], as calculated and simulated, shows that the electron density at the Fe center decreases, while that at the Ni center increases.…”