A Sensitive Method to Monitor Trace Quantities of Benzanthrone in Workers of Dyestuff Industries

Abstract

Dyestuff workers coming in contact with benzanthrone (an intermediate used for the synthesis of a variety of dyes) develop skin lesions, gastritis, liver malfunctions, and sexual disturbances. A highly sensitive fluorometric method to monitor trace quantities of benzanthrone in urine, serum, and biological tissues for experimental studies, has been developed. Coupled with simple extraction and resolution, optimum fluorescence is obtained in an equal mixture of chloroform:methanol, detecting as low as 2 ng benzanthrone. This method is approximately 250 times more sensitive than currently available colorimetric assay.

Allergic contact dermatitis caused by benzanthrone in a pair of trousers

“…It has luminescent properties, and shows brilliant fluorescence. Benzanthrone has been reported to cause systemic symptoms from the gastrointestinal tract, liver malfunction, and skin lesions (15)(16)(17). Regarding skin lesions, benzanthrone has been reported to cause dermal toxicity (18), phototoxicity, and, possibly, photoallergic reactions (8,19,20).…”

PM-bound polycyclic aromatic compounds (PACs) in two large-scale petrochemical bases in South China: Spatial variations, sources, and risk assessment

“…OPAHs are not only pollutants emitted from combustion sources, but also important aromatic products produced by the petrochemical industry. Factor 4 is mainly weighted by 1-PyCHO (71.7%), 6H-BcdP (64.0%), BEZO (50.9%), and ANTQ (39.3%), the important aromatic products that are widely used in dyeing, coating, and organic synthesis industries (Joshi et al 1986;Kajiwara et al 2014;). Therefore, it was designated as a source related to the aromatic industry, and contributed about 20.1% of ∑PACs.…”