A sensitive paper-based sensor for fluoride detection in water using Tb<sup>3+</sup> photoluminescence

Chaturvedi, Pankaj Kumar; Maitra, Uday

doi:10.1039/d4sd00078a

Sens. Diagn.

2024

DOI: 10.1039/d4sd00078a

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A sensitive paper-based sensor for fluoride detection in water using Tb³⁺ photoluminescence

Pankaj Kumar Chaturvedi,

Uday Maitra

Abstract: Fluoride is a vital trace mineral for healthy bones and teeth, but a higher intake can lead to nephrolithiasis, dental/skeletal fluorosis, etc. Many dry regions worldwide contain higher fluoride than...

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Cited by 3 publications

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A Supramolecular Gel‐Based Protocol for the Detection of α‐Glycosidases for Screening Potential Drugs

Sakthivel,

Chaturvedi,

Maitra

2024

Chemistry An Asian Journal

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α‐Glycosidases are carbohydrate‐digesting enzymes that catalyze the hydrolysis of α‑1,4‑glycopyranoside bonds from oligosaccharides and disaccharides. α‑Glucosidase is an important biomarker for the diagnosis of type‑II diabetes, Azoospermia and Pompe diseases. Additionally, mutations in α‑galactosidase lead to Fabry disease. Inhibitors targeting these enzymes are prescribed as anti‐diabetic medications and as effective chaperones for Fabry disease. Comprehending the function and regulation of α‑glycosidases requires accurate quantification methods. In this work, we highlight the design of a simple luminescent ‘turn‐on’ assay for sensing these two α‐glycosidases in a supramolecular TbCh hydrogel matrix using 1‐α‐glycosides as pro‑sensitizers. Our protocol offers a simpler and cost‐effective method for selectively sensing the detection limit of the subnanomolar range of α‐glycosidases. Importantly, the developed enzyme sensors functioned as a platform for rapid screening of drug molecules based on their inhibition potency. Therefore, the protocol is useful for facilitating the development of therapeutics and diagnostics for this important class of enzymes.

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A Supramolecular Gel‐Based Protocol for the Detection of α‐Glycosidases for Screening Potential Drugs

Sakthivel,

Chaturvedi,

Maitra

2024

Chemistry An Asian Journal

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A novel fluorescent probe based on coumarin and triazole for monitoring fluoride ions in the substitution reaction

Liu,

Sun

et al. 2024

Tetrahedron

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Off–On Pathway Complexity in Self-Assembly of Cadmium Cholate Hydrogel with Topological Evolution Triggered by Secondary Nucleation

Sahu,

Seth,

George

et al. 2024

Chem. Mater.

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Tuning supramolecular hierarchical structures based on a meticulous mechanistic understanding has been a less-explored area of supramolecular chemistry. We have serendipitously discovered that the hydrogelation of cadmium cholate involves an unusual process involving the transformation of an initially formed turbid suspension to an opaque gel via a transparent gel. Microscopic investigation revealed an evolution of diverse nanostructures as a function of time, suggesting a pathway complexity involved during the self-assembly process. The initial transformation from a suspension to a transparent gel occurs via an off-pathway mechanism. The subsequent change from a transparent to an opaque gel, interestingly, follows an on-pathway aggregation process. This shift from off-to on-pathway mechanisms directly influenced the crystallinity and mechanical stiffness of the hydrogel. A thorough analysis of the underlying pathway complexity has led us to an unprecedented facet of synthetic supramolecular self-assembly.

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A sensitive paper-based sensor for fluoride detection in water using Tb³⁺ photoluminescence

Abstract: Fluoride is a vital trace mineral for healthy bones and teeth, but a higher intake can lead to nephrolithiasis, dental/skeletal fluorosis, etc. Many dry regions worldwide contain higher fluoride than...

Cited by 3 publications

References 54 publications

A Supramolecular Gel‐Based Protocol for the Detection of α‐Glycosidases for Screening Potential Drugs

A Supramolecular Gel‐Based Protocol for the Detection of α‐Glycosidases for Screening Potential Drugs

A novel fluorescent probe based on coumarin and triazole for monitoring fluoride ions in the substitution reaction

Off–On Pathway Complexity in Self-Assembly of Cadmium Cholate Hydrogel with Topological Evolution Triggered by Secondary Nucleation

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A sensitive paper-based sensor for fluoride detection in water using Tb3+ photoluminescence

Abstract: Fluoride is a vital trace mineral for healthy bones and teeth, but a higher intake can lead to nephrolithiasis, dental/skeletal fluorosis, etc. Many dry regions worldwide contain higher fluoride than...

Cited by 3 publications

References 54 publications

A Supramolecular Gel‐Based Protocol for the Detection of α‐Glycosidases for Screening Potential Drugs

A Supramolecular Gel‐Based Protocol for the Detection of α‐Glycosidases for Screening Potential Drugs

A novel fluorescent probe based on coumarin and triazole for monitoring fluoride ions in the substitution reaction

Off–On Pathway Complexity in Self-Assembly of Cadmium Cholate Hydrogel with Topological Evolution Triggered by Secondary Nucleation

Contact Info

Product

Resources

About

A sensitive paper-based sensor for fluoride detection in water using Tb³⁺ photoluminescence