To adapt to the requirements of diversified development of modern education and the multi-modal communication between teachers and students, now high-techs and multi-modality have been introduced into the cultivation of the Multiple Practical Ability (MPA). However, existing studies on multimodal teaching generally focus on college students or high school students, few have concerned about the teaching design of practical ability cultivation under the synergy of different modalities. Therefore, to fill in this research blank, this paper took English teaching as an example to research the cultivation of MPA under the Multimodal Blended Teaching (MBT) mode. At first, this paper gave a flow chart of MBT and constructed a framework for the teaching modality system of MPA cultivation. Then, a Super-Efficiency Slacks-Based Measure (SE-SBM) model with objectively assigned combinatorial weights was established for evaluating the cultivation effect of students’ MPA, and the said cultivation effect under the MBT mode was analyzed in detail. At last, the effectiveness of the proposed model was verified via experiment, and the analysis results of the differences in the MPA cultivation of students under different conditions were given.