A serological study of Leishmania infantum in dogs of Khorasan Razavi province, Iran

Sabzevari, Sadaf; Razmi, Gholam Reza; Naghibi, Abolghasem; Khoshnegah, Javad

doi:10.1007/s12639-012-0160-x

Cited by 5 publications

(3 citation statements)

References 12 publications

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“…In addition, it may be related to higher CO2 production, attracting vector insects [76,89,217,221], which is also observed in bigger dogs as they have a larger contact area, making them more susceptible to bites [38,157,222]. In relation to sex, several authors found no difference between male and female with the risk of infection [182,183,189,210,[223][224][225].…”

Section: Figurementioning

confidence: 99%

Global Distribution of Canine Visceral Leishmaniasis and the Role of the Dog in the Epidemiology of the Disease

Vilas-Boas,

Nakasone,

Gonçalves

et al. 2024

Preprint

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Visceral leishmaniasis is a disease caused by protozoa of the species Leishmania (Leishmania) infantum (syn=Leishmania chagasi) and Leishmania (Leishmania) donovani, which are transmitted by hematophagous in-sects of the genera Lutzomyia and Phlebotomus. The domestic dog (Canis familiaris) is considered the main ur-ban reservoir of the parasite due to the high parasite load on its skin, serving as a source of infection for sand-fly vectors and, consequently, perpetuating the disease in the urban environment. Some factors are consid-ered important in the perpetuation and spread of canine visceral leishmaniasis (CVL) in urban areas, such as stray dogs with their errant behavior and houses that have backyards with trees, shade, and organic materi-als, creating an attractive environment for sandfly vectors. CVL is found in approximately 50 countries with the number of infected dogs reaching millions and, due to the difficulty of controlling and diagnosing the disease, the number of infected animals could be even greater. In the four continents endemic for CVL there are reports of disease expansion in endemic countries such as Brazil, Italy, Morocco, and Tunisia, as well as in areas where CVL is not endemic, for example, Uruguay. Socio-environmental factors, such as migration, drought, deforestation, and global warming, have been pointed out as one of the reasons for expansion to ar-eas where it had been absent. Thus, the objective of this review is to address (i) the distribution of CVL in endemic areas (ii) the role of the dog in the visceral leishmaniasis epidemiology and the factors that influence dog infection and spread of the disease, and (iii) the challenges faced in the control of CVL.

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Section: Figurementioning

confidence: 99%

Global Distribution of Canine Visceral Leishmaniasis and the Role of the Dog in the Epidemiology of the Disease

Vilas-Boas,

Nakasone,

Gonçalves

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…This is also observed in larger dogs, as they have a larger contact area, making them more susceptible to bites [ 38 , 130 , 195 ]. In relation to sex, several authors found no difference between males and females regarding the risk of infection [ 152 , 153 , 159 , 181 , 196 , 197 , 198 ].…”

Section: Factors Influencing the Territorial Expansion And Transmissi...mentioning

confidence: 99%

Global Distribution of Canine Visceral Leishmaniasis and the Role of the Dog in the Epidemiology of the Disease

Vilas-Boas,

Nakasone,

Gonçalves

et al. 2024

Pathogens

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Visceral leishmaniasis is a disease caused by protozoa of the species Leishmania (Leishmania) infantum (syn = Leishmania chagasi) and Leishmania (Leishmania) donovani, which are transmitted by hematophagous insects of the genera Lutzomyia and Phlebotomus. The domestic dog (Canis familiaris) is considered the main urban reservoir of the parasite due to the high parasite load on its skin, serving as a source of infection for sandfly vectors and, consequently, perpetuating the disease in the urban environment. Some factors are considered important in the perpetuation and spread of canine visceral leishmaniasis (CVL) in urban areas, such as stray dogs, with their errant behavior, and houses that have backyards with trees, shade, and organic materials, creating an attractive environment for sandfly vectors. CVL is found in approximately 50 countries, with the number of infected dogs reaching millions. However, due to the difficulty of controlling and diagnosing the disease, the number of infected animals could be even greater. In the four continents endemic for CVL, there are reports of disease expansion in endemic countries such as Brazil, Italy, Morocco, and Tunisia, as well as in areas where CVL is not endemic, for example, Uruguay. Socio-environmental factors, such as migration, drought, deforestation, and global warming, have been pointed out as reasons for the expansion into areas where it had been absent. Thus, the objective of this review is to address (i) the distribution of CVL in endemic areas, (ii) the role of the dog in the visceral leishmaniasis epidemiology and the factors that influence dog infection and the spread of the disease, and (iii) the challenges faced in the control of CVL.

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“…Approximately every year 500,000 new cases of VL occur in the world (Barati et al 2015;Ghatee et al 2013). In the zoonotic pattern, reservoirs are dogs and rodents (Postigo 2010;Reithinger et al 2007;Sabzevari et al 2013). Evidence has shown that dogs can act as a natural host for MVL, and human is its accidental host (Fig.…”

Section: Introductionmentioning

confidence: 99%

Using proteomics as a powerful tool to develop a vaccine against Mediterranean visceral leishmaniasis

2018

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Visceral leishmaniasis (VL) is a tropical infectious disease, which is called Mediterranean visceral leishmaniasis (MVL) in the Mediterranean area. In spite of many attempts, no effective commercial vaccine exists for MVL. To find new targets for developing antileishmanial vaccines, knowing parasite antigens that provoke the immune system are on demand. Nowadays, proteomics methods are defined as approaches for analysis of protein profiling of different cells. Within this framework, detection of new antigens is becoming more facilitated. In this review, we aimed to introduce possible targets using proteomics so; they could be used as candidates for developing vaccines against MVL. It can shed new light in the near future on the development of promising vaccines for MVL.

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A serological study of Leishmania infantum in dogs of Khorasan Razavi province, Iran

Cited by 5 publications

References 12 publications

Global Distribution of Canine Visceral Leishmaniasis and the Role of the Dog in the Epidemiology of the Disease

Global Distribution of Canine Visceral Leishmaniasis and the Role of the Dog in the Epidemiology of the Disease

Global Distribution of Canine Visceral Leishmaniasis and the Role of the Dog in the Epidemiology of the Disease

Using proteomics as a powerful tool to develop a vaccine against Mediterranean visceral leishmaniasis

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