“…Blob/tubular detection refers to methods that are aimed at detecting clustered points in the image that are either brighter or darker than the surrounding region. The shape-based object detection in images is an important step in the analysis of large-scale scientific data, as for example: satellite and Unmanned Aerial Vehicles (UAVs) images for human, fire and building detection, lakes detection from radiometric and geometric rectified Landsat Multispectral Scanner (MSS) images and Thematic Mapper (TM) images, light points detection, blob detection in infrared images, medical imaging and others [9,17,29,37]. In the medical imaging context, the detection of bleeding/blood regions in WCE images, bright lesions in fundus images, nodule detection in thorax X-ray images, nuclei detection in microscopic zebrafish images, enhancement of vascular structures, detection of lesions in images of multiple sclerosis patients, tumor detection based on blob detection, [10,12,14,16,22,27,32,39] represent some of the examples addressed by the community.…”