A Short History of Diphtheria

Roddis, Louis H.

doi:10.1093/milmed/120.1.51

Military Medicine

1957

DOI: 10.1093/milmed/120.1.51

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A Short History of Diphtheria

Louis H. Roddis¹

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“…Another infectious disease mentioned in several files is diphtheria, a disease long gone from Western countries due to vaccination. This is a potentially fatal disease of the airways causing obstruction and death if the membrane occluding the airways is not removed [4]. Modern treatment of diphtheria is with antibiotics and an antitoxin.…”

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confidence: 99%

Risky Business: A Comment on Nurse’s Exposure to Infectious Diseases at Work, the Experiences of WW1 Nurses from New Zealand

2024

Infect Dis Ther

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confidence: 99%

Risky Business: A Comment on Nurse’s Exposure to Infectious Diseases at Work, the Experiences of WW1 Nurses from New Zealand

2024

Infect Dis Ther

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The 1925 Diphtheria Antitoxin Run to Nome - Alaska: A Public Health Illustration of Human-Animal Collaboration

2016

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Diphtheria is an acute toxin-mediated superficial infection of the respiratory tract or skin caused by the aerobic gram-positive bacillus Corynebacterium diphtheriae. The epidemiology of infection and clinical manifestations of the disease vary in different parts of the world. Historical accounts of diphtheria epidemics have been described in many parts of the world since antiquity. Developed in the late 19th century, the diphtheria antitoxin (DAT) played a pivotal role in the history of public health and vaccinology prior to the advent of the diphtheria-tetanus toxoids and acellular pertussis (DTaP) vaccine. One of the most significant demonstrations of the importance of DAT was its use in the 1925 diphtheria epidemic of Nome, Alaska. Coordinated emergency delivery of this life-saving antitoxin by dog-sled relay in the harshest of conditions has left a profound legacy in the annals of vaccinology and public health. Lead dogs Balto and Togo, and the dog-led antitoxin run of 1925 represent a dynamic illustration of the contribution made by non-human species towards mass immunization in the history of vaccinology. This unique example of cooperative interspecies fellowship and collaboration highlights the importance of the human-animal bond in the one-health initiative.

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A Short History of Diphtheria

Cited by 2 publications

References 0 publications

Risky Business: A Comment on Nurse’s Exposure to Infectious Diseases at Work, the Experiences of WW1 Nurses from New Zealand

Risky Business: A Comment on Nurse’s Exposure to Infectious Diseases at Work, the Experiences of WW1 Nurses from New Zealand

The 1925 Diphtheria Antitoxin Run to Nome - Alaska: A Public Health Illustration of Human-Animal Collaboration

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